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   Articles with "lactic glycolic" as a keyword



PINK1 siRNA‐loaded poly(lactic‐co‐glycolic acid) nanoparticles provide neuroprotection in a mouse model of photothrombosis‐induced ischemic stroke

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recommendations! Published in 2023 at "Glia"

DOI: 10.1002/glia.24339

Abstract: PTEN‐induced kinase 1 (PINK1) is a well‐known critical marker in the pathway for mitophagy regulation as well as mitochondrial dysfunction. Evidence suggests that mitochondrial dynamics and mitophagy flux play an important role in the development… read more here.

Keywords: ischemic stroke; poly lactic; lactic glycolic; pink1 ... See more keywords

Preparation of Poly(lactic-co-glycolic acid)-Based Composite Microfibers for Postoperative Treatment of Tumor in NIR I and NIR II Biowindows.

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recommendations! Published in 2018 at "Macromolecular bioscience"

DOI: 10.1002/mabi.201800206

Abstract: In this work, a novel kind of electrospun microfiber to deliver a photothermal agent and an anticancer drug to tumor sites is explored. Photothermal therapy agent (MoS2 nanosheets) and doxorubicin (DOX) are incorporated with poly(lactic-co-glycolic… read more here.

Keywords: composite microfibers; poly lactic; lactic glycolic; nir biowindows ... See more keywords

Enhanced Poly(Lactic‐Co‐Glycolic Acid) Composite for Bone Tissue Repair Applications: A Comprehensive Optimization Approach

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recommendations! Published in 2025 at "Macromolecular Materials and Engineering"

DOI: 10.1002/mame.202500084

Abstract: This study explores Poly(lactic‐co‐glycolic acid) (PLGA)‐based scaffolds modified with 10 wt% polycaprolactone (PCL), polylactic acid (PLA), and polyurethane (PU) to enhance their performance. The composite films were characterized by tensile testing, degradability, water absorption, thermal… read more here.

Keywords: lactic glycolic; plga pla; glycolic acid; plga ... See more keywords

Poly(lactic-co-glycolic acid) devices: Production and applications for sustained protein delivery.

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recommendations! Published in 2018 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"

DOI: 10.1002/wnan.1516

Abstract: Injectable or implantable poly(lactic-co-glycolic acid) (PLGA) devices for the sustained delivery of proteins have been widely studied and utilized to overcome the necessity of repeated administrations for therapeutic proteins due to poor pharmacokinetic profiles of… read more here.

Keywords: poly lactic; production; delivery; biology ... See more keywords

Long acting injectable formulations: the state of the arts and challenges of poly(lactic-co-glycolic acid) microsphere, hydrogel, organogel and liquid crystal

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recommendations! Published in 2019 at "Journal of Pharmaceutical Investigation"

DOI: 10.1007/s40005-019-00449-9

Abstract: BackgroundLong-acting injectable formulations (LAIFs) have received substantial attention recently due to their advantages over conventional formulations, including easy administration, continuous and controlled release of drug over months, and the ability to maintain drug concentrations within… read more here.

Keywords: poly lactic; injectable formulations; drug; lactic glycolic ... See more keywords

Comparative molecular dynamic simulation study on the use of chitosan for temperature stabilization of interferon αII.

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recommendations! Published in 2019 at "Carbohydrate polymers"

DOI: 10.1016/j.carbpol.2018.09.032

Abstract: Carbohydrate biopolymer of biocompatible biodegradable chitosan, currently become one of the most usable polymer in medical and pharmaceutical sciences. In this regard a large number of protein and peptide drugs are used as therapeutic agents… read more here.

Keywords: protein; poly lactic; temperature; interferon ... See more keywords

Ciprofloxacin‐loaded sodium alginate/poly (lactic‐co‐glycolic acid) electrospun fibrous mats for wound healing

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recommendations! Published in 2018 at "European Journal of Pharmaceutics and Biopharmaceutics"

DOI: 10.1016/j.ejpb.2017.11.004

Abstract: Graphical abstract Figure. No Caption available. Abstract Wound dressings should ideally be able to maintain high humidity, remove excess wound exudate, permit thermal insulation, provide certain mechanical strength, and in some cases deliver antibiotics to… read more here.

Keywords: poly lactic; ciprofloxacin; sodium alginate; lactic glycolic ... See more keywords

Electrosprayed poly(lactic-co-glycolic acid) particles as a promising drug delivery system for the novel JNK inhibitor IQ-1.

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recommendations! Published in 2020 at "European polymer journal"

DOI: 10.1016/j.eurpolymj.2020.109598

Abstract: Mitogen-activated protein kinases (MAPKs), including c-Jun N-terminal kinase (JNK), play important role in the regulation of pro-inflammatory cytokine secretion and signaling cascades. Therefore, JNKs are key targets for the treatment of cytokine/JNK-driven diseases. Herein, we… read more here.

Keywords: poly lactic; jnk; novel jnk; jnk inhibitor ... See more keywords

pH-responsive Astragalus polysaccharides-loaded poly(lactic-co-glycolic acid) nanoparticles and their in vitro immunogenicity.

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recommendations! Published in 2019 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2018.12.156

Abstract: Astragalus polysaccharides (APS) have long been well known as immune boosters, but have not been fully exploited in clinical settings. Here, poly(lactic-co-glycolic acid) (PLGA) was used to form a nanocarrier for APS to enhance its… read more here.

Keywords: poly lactic; astragalus polysaccharides; responsive apsps; lactic glycolic ... See more keywords

Enhanced cell viability in hyaluronic acid coated poly(lactic-co-glycolic acid) porous scaffolds within microfluidic channels.

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recommendations! Published in 2017 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2017.09.053

Abstract: The concept of the present work is to produce porous optimised scaffolds of poly(lactic-co-glycolic acid) (PLGA) coated with hyaluronic acid (HA), to provide a suitable microenvironment for cellular proliferation. Freeze dried scaffolds were produced from… read more here.

Keywords: poly lactic; within microfluidic; hyaluronic acid; lactic glycolic ... See more keywords

The mechanism behind the biphasic pulsatile drug release from physically mixed poly(dl‐lactic(‐co‐glycolic) acid)‐based compacts

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recommendations! Published in 2018 at "International Journal of Pharmaceutics"

DOI: 10.1016/j.ijpharm.2018.09.025

Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Successful immunization often requires a primer, and after a certain lag time, a booster administration of the antigen. To improve the vaccinees’ comfort and compliance, a single‐injection vaccine… read more here.

Keywords: poly lactic; mechanism; drug; biphasic pulsatile ... See more keywords