The Influence of Arginine and Counter-Ions: Antibody Stability during Freeze-Drying.
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DOI: 10.1016/j.xphs.2020.12.009
Abstract: Amino acids, for example L-arginine, are used in lyophilisation as crystalline bulking, buffering, viscosity reducing or stabilising excipients. In this study, arginine was formulated with different counter ions (hydrochloride, citrate, lactobionate, phosphate, and succinate). A… read more here.
Keywords: antibody; arginine; protein stability; lactobionate ... See more keywords