In vivo study of the effect of lactoferrin on iron metabolism and bioavailability from different iron chemical species for formula milk fortification
Sign Up to like & getrecommendations! Published in 2018 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700231
Abstract: Iron fortification in infant formulas is a common practice for providing iron to newborns in order to avoid its deficiency (anemia). Depending on the physicochemical species used, its bioavailability might be insufficient to meet iron… read more here.
Keywords: bioavailability; lactoferrin; formula milk; fortification ... See more keywords
Transport of Human Lactoferrin into Mouse Brain: Administration Routes and Distribution
Sign Up to like & getrecommendations! Published in 2019 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-019-04572-3
Abstract: We studied different ways of transport of human lactoferrin to the brain of C57Bl/6 mice after its administration via different routes, analyzed its distribution in the brain, and determined the phenotype of lactoferrin-containing cells. Colocalization… read more here.
Keywords: administration; mouse brain; lactoferrin; human lactoferrin ... See more keywords
Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities
Sign Up to like & getrecommendations! Published in 2020 at "Investigational New Drugs"
DOI: 10.1007/s10637-020-01020-2
Abstract: Lactoferrin has gained extensive attention due to its ample biological properties. In this study, recombinant human lactoferrin carrying humanized glycosylation (rhLf-h-glycan) expressed in the yeast Pichia pastoris SuperMan5, which is genetically glycoengineered to efficiently produce… read more here.
Keywords: recombinant human; apoptosis; lactoferrin; cytotoxicity ... See more keywords
Effects of recombinant human lactoferrin on calcium signaling and functional responses of human neutrophils.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.108122
Abstract: Lactoferrin is a non-heme iron-binding glycoprotein with multiple health-beneficial functions including antimicrobial, antioxidant, anticarcinogenic, and immunomodulatory effects. There is emerging evidence that neutrophils may serve as targets of lactoferrin in vivo, and here we show… read more here.
Keywords: recombinant human; lactoferrin; human lactoferrin; human neutrophils ... See more keywords
Lactoferrin and lactoferricin B reduce adhesion and biofilm formation in the intestinal symbionts Bacteroides fragilis and Bacteroides thetaiotaomicron.
Sign Up to like & getrecommendations! Published in 2020 at "Anaerobe"
DOI: 10.1016/j.anaerobe.2020.102232
Abstract: Several factors affect the composition of species that inhabit our intestinal tract, including mode of delivery, genetics and nutrition. Antimicrobial peptides and proteins secreted in the gastrointestinal tract are powerful tools against bacteria. Lactoferrin (LF)… read more here.
Keywords: biofilm formation; tract; lactoferrin; bacteroides fragilis ... See more keywords
In vitro effectiveness of recombinant human lactoferrin and its hydrolysate in alleviating LPS-induced inflammatory response.
Sign Up to like & getrecommendations! Published in 2019 at "Food research international"
DOI: 10.1016/j.foodres.2017.12.029
Abstract: This study aimed to evaluate the potential anti-inflammatory role of the most produced form of lactoferrin expressed in various expression systems (Fe-saturated recombinant human Lf, rhLf) and its hydrolysate in concentrations resembles that found in… read more here.
Keywords: recombinant human; vitro effectiveness; lactoferrin; hydrolysate ... See more keywords
Impact of maternal nutrition during early pregnancy and diet during lactation on lactoferrin in mature breast milk.
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition"
DOI: 10.1016/j.nut.2021.111500
Abstract: OBJECTIVE Lactoferrin supplementation is a promising strategy to prevent infections in neonates. Exploring whether maternal nutritional status in early pregnancy and maternal diet during lactation are associated with lactoferrin concentrations in mature human milk can… read more here.
Keywords: milk; early pregnancy; lactoferrin; diet lactation ... See more keywords
Aggregation of Lactoferrin Caused by Droplet Atomization Process via a Two-Fluid Nozzle: The Detrimental Effect of Air-Water Interfaces.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00358
Abstract: Biological macromolecules, especially therapeutic proteins, are delicate and highly sensitive to denaturation from stresses encountered during the manufacture of dosage forms. Thin-film freeze-drying (TFFD) and spray freeze-drying (SFD) are two processes used to convert liquid… read more here.
Keywords: water; air; lactoferrin; two fluid ... See more keywords
Effects of thermal treatment on the physicochemical properties and osteogenic activity of lactoferrin
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Food Processing and Preservation"
DOI: 10.1111/jfpp.14068
Abstract: Lactoferrin as a key basic protein in bovine milk has attracted extensive attentions due to its multifunctional activities. Thermal treatment has been widely used during processing of dairy products, which might damage the bioactivity of… read more here.
Keywords: activity lactoferrin; osteogenic activity; thermal treatment; lactoferrin ... See more keywords
Effects of free and nano‐encapsulated bovine lactoferrin on the viability and acid production by Streptococcus mutans biofilms
Sign Up to like & getrecommendations! Published in 2022 at "Letters in Applied Microbiology"
DOI: 10.1111/lam.13796
Abstract: Tooth decay is one of the most common diseases that humans face during their lifetime. Streptococcus mutans is one of the most critical factors of early tooth decay. These bacteria may produce biofilms in the… read more here.
Keywords: streptococcus mutans; lactoferrin; acid; acid production ... See more keywords
The Antimicrobial Bifunctional Camel Lactoferrin: In Silico and Molecular Dynamic Perspective
Sign Up to like & getrecommendations! Published in 2023 at "BioMed Research International"
DOI: 10.1155/2023/2322286
Abstract: Lactoferrin (LF) is a major natural antimicrobial agent secreted in body fluids as a natural innate immunity protein. The action and structure of LF are closely related to its iron-binding capacity with structural reporting in… read more here.
Keywords: clf; lactoferrin; antimicrobial bifunctional; bifunctional camel ... See more keywords