The Structural Determinants Accounting for the Broad Substrate Specificity of the Quorum Quenching Lactonase GcL
Sign Up to like & getrecommendations! Published in 2019 at "ChemBioChem"
DOI: 10.1002/cbic.201900024
Abstract: Quorum quenching lactonases are enzymes capable of hydrolyzing lactones, including N‐acyl homoserine lactones (AHLs). AHLs are molecules known as signals in bacterial communication dubbed quorum sensing. Bacterial signal disruption by lactonases was previously reported to… read more here.
Keywords: broad substrate; lactonase; quorum quenching; substrate specificity ... See more keywords
Extracellular lactonase mediated quorum quenching by a novel Bacillus velezensis.
Sign Up to like & getrecommendations! Published in 2022 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fnac095
Abstract: Many Gram-negative bacteria coordinate their gene expression via quorum sensing (QS) mediated by small diffusible autoinducer molecules such as Acyl Homoseriene Lactones (AHL). The degradation of AHLs or quorum quenching (QQ) imparts less selection pressure… read more here.
Keywords: quorum quenching; bacillus velezensis; lactonase; gram negative ... See more keywords
Mining Marine Metagenomes Revealed a Quorum-Quenching Lactonase with Improved Biochemical Properties That Inhibits the Food Spoilage Bacterium Pseudomonas fluorescens
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DOI: 10.1128/aem.01680-21
Abstract: Our results emphasize the potential of sequence and structure-based identification of new QQ enzymes from environmental metagenomes, such as from the ocean, with improved stability or activity. The findings also suggest that purified QQ enzymes… read more here.
Keywords: food spoilage; biochemical properties; food; lactonase ... See more keywords
Characterization of a novel N-acylhomoserine lactonase, AidP, from Antarctic Planococcus sp.
Sign Up to like & getrecommendations! Published in 2018 at "Microbial Cell Factories"
DOI: 10.1186/s12934-018-1024-6
Abstract: BackgroundN-acylhomoserine lactones (AHLs) are well-studied signalling molecules produced by some Gram-negative Proteobacteria for bacterial cell-to-cell communication or quorum sensing. We have previously demonstrated the degradation of AHLs by an Antarctic bacterium, Planococcus versutus L10.15T, at… read more here.
Keywords: ahl lactonase; analysis; lactonase; quorum sensing ... See more keywords