Articles with "lactone core" as a keyword



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Molecular docking study of GSK‐3β interaction with nomilin, kihadanin B, and related limonoids and triterpenes with a furyl‐δ‐lactone core

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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23130

Abstract: Glycogen synthase kinase‐3β (GSK‐3β) is a target enzyme considered for the treatment of multiple human diseases, from neurodegenerative pathologies to viral infections and cancers. Numerous inhibitors of GSK‐3β have been discovered but thus far only… read more here.

Keywords: furyl lactone; natural products; gsk; lactone core ... See more keywords