Identification of lactylation related model to predict prognostic, tumor infiltrating immunocytes and response of immunotherapy in gastric cancer
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DOI: 10.3389/fimmu.2023.1149989
Abstract: Background The epigenetic regulatory chemical lactate is a product of glycolysis. It can regulate gene expression through histone lactylation, thereby promoting tumor proliferation, metastasis, and immunosuppression. Methods In this study, a lactylation-related model for gastric… read more here.
Keywords: response; lactylation related; related model; lactylation ... See more keywords
Lactylation-Related Gene Signature Effectively Predicts Prognosis and Treatment Responsiveness in Hepatocellular Carcinoma
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DOI: 10.3390/ph16050644
Abstract: Background: Hepatocellular carcinoma (HCC) is a malignant tumor associated with high morbidity and mortality. Therefore, it is of great importance to develop effective prognostic models and guide clinical treatment in HCC. Protein lactylation is found… read more here.
Keywords: gene signature; treatment; lactylation related; lactylation ... See more keywords