Blocking MMP-12-modulated epithelial-mesenchymal transition by repurposing penfluridol restrains lung adenocarcinoma metastasis via uPA/uPAR/TGF-β/Akt pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular oncology"
DOI: 10.1007/s13402-021-00620-1
Abstract: PURPOSE Metastasis of lung adenocarcinoma (LADC) is a crucial factor determining patient survival. Repurposing of the antipsychotic agent penfluridol has been found to be effective in the inhibition of growth of various cancers. As yet,… read more here.
Keywords: lung adenocarcinoma; ladc cells; mmp; metastasis ... See more keywords