Review of Talimogene Laherparepvec (T-VEC): A First in Class Oncolytic Viral Treatment of Advanced Melanoma.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2020.01.039
Abstract: Talimogene laherparepvec (T-VEC) is an oncolytic virus based on herpes simplex virus type-1 approved for intralesional treatment of advanced melanoma. In this article, we review the clinical literature on T-VEC for advanced melanoma and provide… read more here.
Keywords: advanced melanoma; talimogene laherparepvec; treatment advanced; laherparepvec vec ... See more keywords
Reversing resistance to PD-1 blockade by combination of talimogene laherparepvec (T-VEC) with pembrolizumab (pembro) in advanced melanoma patients following progression on a prior PD-1 inhibitor: SWOG S1607 (NCT#02965716).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.tps9603
Abstract: TPS9603Background: A significant number of patients do not respond to PD-1/L1 blockade because there are no pre-existing tumor antigen-specific T-cells in their tumors ready to attack the cancer. W... read more here.
Keywords: resistance blockade; talimogene laherparepvec; laherparepvec vec; reversing resistance ... See more keywords