Low appendicular muscle mass is associated with mortality in peritoneal dialysis patients: a single-center cohort study
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Clinical Nutrition"
DOI: 10.1038/ejcn.2017.104
Abstract: Background/Objectives:There are few studies of the association between low appendicular muscle mass (LAM) and clinical outcomes in peritoneal dialysis (PD) patients. We aimed to determine the clinical association between LAM and clinical outcomes in PD… read more here.
Keywords: lam; appendicular muscle; mass; muscle mass ... See more keywords
A new 1 : 1 cocrystal of lamotrigine and 1,2,3,6-hydrophthalimide: discovery, characterization, and construction of ternary phase diagrams
Sign Up to like & getrecommendations! Published in 2020 at "CrystEngComm"
DOI: 10.1039/d0ce00178c
Abstract: A 1 : 1 cocrystal of lamotrigine (LAM) and 1,2,3,6-hydrophthalimide (HPHT) was successfully synthesized for the first time and was characterized by XRD (powder and single-crystal X-ray diffraction), FT-IR, DSC and TG. Molecular Hirshfeld surfaces and the… read more here.
Keywords: cocrystal lamotrigine; lam; ternary phase; solubility ... See more keywords
Prospective nanoparticle treatments for lymphangioleiomyomatosis
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Delivery"
DOI: 10.1080/17425247.2022.2029401
Abstract: ABSTRACT Introduction Lymphangioleiomyomatosis (LAM) is a rare lung disease that is characterized by smooth muscle-like cell growth in the lungs. The current available oral treatment rapamycin slows down the disease progression but does not result… read more here.
Keywords: prospective nanoparticle; treatments lymphangioleiomyomatosis; lam; nanoparticle treatments ... See more keywords
Clinic-Based Urinary Lipoarabinomannan as a Biomarker of Clinical Disease Severity and Mortality Among Antiretroviral Therapy-Naive Human Immunodeficiency Virus-Infected Adults in South Africa
Sign Up to like & getrecommendations! Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx167
Abstract: Abstract Background Urinary lipoarabinomannan (LAM) has limited sensitivity for diagnosing active human immunodeficiency virus (HIV)-associated tuberculosis (TB) disease, but LAM screening at HIV diagnosis might identify adults with more severe clinical disease or greater risk… read more here.
Keywords: clinical disease; lam; disease; mortality ... See more keywords
PERFORMANCE OF XPERT MTB/RIF AND DETERMINE LAM IN HIV-INFECTED ADULTS IN PERI-URBAN SITES IN ZAMBIA (CDC OP-X STUDY)
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Global Health"
DOI: 10.1136/bmjgh-2016-000260.14
Abstract: Background Tuberculosis (TB) mortality in HIV-infected patients remains high in sub-Saharan Africa. Inadequate diagnostic tools delay time to TB treatment. Methods A two-phase TB diagnostic study was conducted among HIV-infected adult patients from 2014–2016. Patients… read more here.
Keywords: lam; treatment; hiv; culture ... See more keywords
Phenotypic characterization of primary non-nodular and nodular lymphangeioleiomyomatosis (LAM) cells
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5729564
Abstract: Background: Lymphangioleiomyomatosis (LAM) is a rare lung disease that predominantly develops in women between the ages of 20–40 years. The main characteristics of LAM are metastatic spread and infiltration of tissues by proliferative, abnormal smooth… read more here.
Keywords: non nodular; nodular lam; lam cells; physiology ... See more keywords
HOX/PBX Inhibition Attenuates Tsc2-Null Cell Viability and Lung Metastasis in Lymphangioleiomyomatosis
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5732717
Abstract: Lymphangioleiomyomatosis (LAM) is a rare lung disease that exclusively affects premenopausal women. LAM is caused by infiltration of metastasizing atypical smooth muscle-like cells into the lungs leading to progressive respiratory failure. Though the origin of… read more here.
Keywords: lam; cell; hox pbx; physiology ... See more keywords
Bioassay-Guided Isolation of Antiplasmodial Compounds from Hypericum lanceolatum Lam. (Hypericaceae) and Their Cytotoxicity and Molecular Docking
Sign Up to like & getrecommendations! Published in 2023 at "BioMed Research International"
DOI: 10.1155/2023/4693765
Abstract: In Cameroon, malaria is still the cause of several deaths yearly and leading to the continued search for new potent leads to fight against Plasmodium falciparum. Medicinal plants like Hypericum lanceolatum Lam. are introduced in… read more here.
Keywords: molecular docking; hypericum lanceolatum; guided isolation; bioassay guided ... See more keywords
Abstract 1230: The pre-metastatic niche establishment through the induction of the epithelial-to-mesenchymal transition by circulating exosomes in lymphangioleiomyomatosis (LAM): implication of the complement cascade
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1230
Abstract: Exosomes are a class of extra cellular vesicles (EVs), with a multi vesicular endosomal origin, that are released by all cell types, with sizes ranging from 30-150nm and a lipid bilayer membrane. They have been… read more here.
Keywords: lymphangioleiomyomatosis lam; derived exosomes; pre metastatic; niche establishment ... See more keywords
Needle in the Haystack: Finding the Elusive Lymphangioleiomyomatosis Cell
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.202006-2436ed
Abstract: In this issue of the Journal, Guo and colleagues (pp. 1373–1387) (1) use state-of-the-art single-cell techniques to provide insights into lymphangioleiomyomatosis (LAM), a rare multisystem disease primarily affecting women, which is characterized by cystic destruction… read more here.
Keywords: expression; lung; lam; cell ... See more keywords
Supporting a Precious Resource: Healthcare Clinicians
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.202009-3576ed
Abstract: LAM pathogenesis to determine druggable targets. The data on the LAM cell, its gene expression pattern, and its effect on its microenvironment were generated with the input of only three LAM lungs owing to the… read more here.
Keywords: lam cell; supporting precious; lam; resource healthcare ... See more keywords