Phenotypic characterization of primary non-nodular and nodular lymphangeioleiomyomatosis (LAM) cells
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5729564
Abstract: Background: Lymphangioleiomyomatosis (LAM) is a rare lung disease that predominantly develops in women between the ages of 20–40 years. The main characteristics of LAM are metastatic spread and infiltration of tissues by proliferative, abnormal smooth… read more here.
Keywords: non nodular; nodular lam; lam cells; physiology ... See more keywords
Needle in the Haystack: Finding the Elusive Lymphangioleiomyomatosis Cell
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.202006-2436ed
Abstract: In this issue of the Journal, Guo and colleagues (pp. 1373–1387) (1) use state-of-the-art single-cell techniques to provide insights into lymphangioleiomyomatosis (LAM), a rare multisystem disease primarily affecting women, which is characterized by cystic destruction… read more here.
Keywords: expression; lung; lam; cell ... See more keywords
Supporting a Precious Resource: Healthcare Clinicians
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DOI: 10.1164/rccm.202009-3576ed
Abstract: LAM pathogenesis to determine druggable targets. The data on the LAM cell, its gene expression pattern, and its effect on its microenvironment were generated with the input of only three LAM lungs owing to the… read more here.
Keywords: lam cell; supporting precious; lam; resource healthcare ... See more keywords
LAM Cells as Potential Drivers of Senescence in Lymphangioleiomyomatosis Microenvironment
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DOI: 10.3390/ijms23137040
Abstract: Senescence is a stress-response process characterized by the irreversible inhibition of cell proliferation, associated to the acquisition of a senescence-associated secretory phenotype (SASP), that may drive pathological conditions. Lymphangioleiomyomatosis (LAM) is a rare disease in… read more here.
Keywords: cells potential; expression; lam cells; senescence ... See more keywords