Laminin-511-derived recombinant fragment and Rho kinase inhibitor Y-27632 facilitate serial cultivation of keratinocytes differentiated from human embryonic stem cells
Sign Up to like & getrecommendations! Published in 2021 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2021.07.004
Abstract: Introduction Keratinocytes derived from pluripotent stem cells have a short proliferative lifespan under conventional culture conditions that are optimized for keratinocytes. Recently, a Rho kinase inhibitor, Y-27632, had been used as a standard supplement for… read more here.
Keywords: serial cultivation; laminin 511; derived keratinocytes; cultivation ... See more keywords
Laminin-511-E8 promotes efficient in vitro expansion of human limbal melanocytes
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DOI: 10.1038/s41598-020-68120-0
Abstract: Limbal melanocytes, located in the basal epithelial layer of the corneoscleral limbus, represent essential components of the corneal epithelial stem cell niche, but, due to difficulties in their isolation and cultivation, their biological roles and… read more here.
Keywords: laminin 511; limbal melanocytes; human limbal; stem cell ... See more keywords
Endothelial Basement Membrane Laminins as an Environmental Cue in Monocyte Differentiation to Macrophages
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DOI: 10.3389/fimmu.2020.584229
Abstract: Monocyte differentiation to macrophages is triggered by migration across the endothelial barrier, which is constituted by both endothelial cells and their underlying basement membrane. We address here the role of the endothelial basement membrane laminins… read more here.
Keywords: laminin 511; basement membrane; monocyte differentiation; differentiation ... See more keywords
Laminin 511-E8 Fragment Offers Superior Adhesion Properties for Gastric Cancer Cells Compared with Full-Length Laminin 511
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DOI: 10.3390/cimb44040105
Abstract: Simple Summary Numerous studies over the past few decades have revealed that the interactions of gastric cancer cells with laminins through integrins play important roles in tumor cell proliferation, infiltration, and metastasis. However, the association… read more here.
Keywords: adhesion; cancer; fragment; gastric cancer ... See more keywords