LAUSR

Lamins Organize the Global Three-Dimensional Genome from the Nuclear Periphery.

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1 Published in 2018 at "Molecular cell"

DOI: 10.1016/j.molcel.2018.05.017

Abstract: Lamins are structural components of the nuclear lamina (NL) that regulate genome organization and gene expression, but the mechanism remains unclear. Using Hi-C, we show that lamins maintain proper interactions among the topologically associated chromatin… read more here.

Keywords: nuclear periphery; chromatin domains; genome; lamins organize ... See more keywords