Upregulation of ATF4-LAMP3 Axis by ORF45 Facilitates Lytic Replication of Kaposi’s Sarcoma-Associated Herpesvirus
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DOI: 10.1128/jvi.01456-22
Abstract: The lytic replication of Kaposi’s sarcoma-associated herpesvirus (KSHV) reprograms cellular transcription and translation to generate viral proteins and virion particles. Here, we show that the mediator of ER stress ATF4 and the expression of the… read more here.
Keywords: lytic replication; replication; lamp3; kaposi sarcoma ... See more keywords
Salivary gland LAMP3 mRNA expression is a possible predictive marker in the response to hydroxychloroquine in Sjögren’s disease
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DOI: 10.1371/journal.pone.0282227
Abstract: Hydroxychloroquine (HCQ) is a lysosomotropic agent that is commonly used for treating Sjögren’s disease (SjD). However, its efficacy is controversial because of the divergent response to the drug among patients. In a subgroup of SjD… read more here.
Keywords: lamp3 mrna; disease; expression; lamp3 ... See more keywords
LAMP3 promotes the invasion of osteosarcoma cells via SPP1 signaling
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DOI: 10.3892/mmr.2017.7349
Abstract: Osteosarcoma is the most common type of primary bone cancer in children and young adults. The prognosis of osteosarcoma is very poor when it is diagnosed with metastasis. Lysosomal-associated membrane protein 3 (LAMP3) is a… read more here.
Keywords: spp1 signaling; osteosarcoma; metastasis; lamp3 ... See more keywords