The Current Landscape of Antibody-based Therapies in Solid Malignancies
Sign Up to like & getrecommendations! Published in 2021 at "Theranostics"
DOI: 10.7150/thno.52614
Abstract: Over the past three decades, monoclonal antibodies (mAbs) have revolutionized the landscape of cancer therapy. Still, this benefit remains restricted to a small proportion of patients due to moderate response rates and resistance emergence. The… read more here.
Keywords: based therapies; landscape antibody; current landscape; mab based ... See more keywords
The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.83442
Abstract: The Omicron BA.1 variant of SARS-CoV-2 escapes convalescent sera and monoclonal antibodies that are effective against earlier strains of the virus. This immune evasion is largely a consequence of mutations in the BA.1 receptor binding… read more here.
Keywords: affinity; binding affinity; sars cov; landscape antibody ... See more keywords