Landscape of drug-resistance mutations in kinase regulatory hotspots
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbaa108
Abstract: More than 48 kinase inhibitors (KIs) have been approved by Food and Drug Administration. However, drug-resistance (DR) eventually occurs, and secondary mutations have been found in the previously targeted primary-mutated cancer cells. Cancer and drug… read more here.
Keywords: drug resistance; drug; mutations kinase; resistance mutations ... See more keywords