Articles with "landscape platinum" as a keyword



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Genomic landscape of platinum resistant and sensitive testicular cancers

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Published in 2020 at "Nature Communications"

DOI: 10.1038/s41467-020-15768-x

Abstract: While most testicular germ cell tumours (TGCTs) exhibit exquisite sensitivity to platinum chemotherapy, ~10% are platinum resistant. To gain insight into the underlying mechanisms, we undertake whole exome sequencing and copy number analysis in 40… read more here.

Keywords: platinum; copy number; landscape platinum; platinum resistant ... See more keywords