pycofitness—Evaluating the fitness landscape of RNA and protein sequences
Sign Up to like & getrecommendations! Published in 2024 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btae074
Abstract: Abstract Motivation The accurate prediction of how mutations change biophysical properties of proteins or RNA is a major goal in computational biology with tremendous impacts on protein design and genetic variant interpretation. Evolutionary approaches such… read more here.
Keywords: fitness landscape; rna; protein; pycofitness evaluating ... See more keywords
Unveiling the functional and evolutionary landscape of RNA editing in chicken using genomics and transcriptomics
Sign Up to like & getrecommendations! Published in 2022 at "Zoological Research"
DOI: 10.24272/j.issn.2095-8137.2022.331
Abstract: The evolutionary and functional features of RNA editing are well studied in mammals, cephalopods, and insects, but not in birds. Here, we integrated transcriptomic and whole-genomic analyses to exhaustively characterize the expansive repertoire of adenosine-to-inosine… read more here.
Keywords: rna editing; landscape rna; unveiling functional; rna ... See more keywords