Langerhans cells and sexual transmission of HIV and HSV
Sign Up to like & getrecommendations! Published in 2017 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.1923
Abstract: Langerhans cells (LCs) situated in stratified squamous epithelium of the skin and mucosal tissue are amongst the first cells that sexually transmitted pathogens encounter during transmission. They are potent antigen presenting cells and play a… read more here.
Keywords: hsv; transmission; hiv; role ... See more keywords
An Ectoderm-Derived Myeloid-like Cell Population Functions as Antigen Transporters for Langerhans Cells in Zebrafish Epidermis.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental cell"
DOI: 10.1016/j.devcel.2019.03.028
Abstract: Tissue-resident macrophages (TRMs) are highly heterogeneous and engage in a wide range of diverse functions. Yet, the heterogeneities of their origins and functions remain incompletely defined. Here, we report the identification and characterization of an… read more here.
Keywords: like cell; derived myeloid; myeloid like; ectoderm derived ... See more keywords
S100 protein-positive Langerhans cells in 80 dentigerous cysts
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Dental Sciences"
DOI: 10.1016/j.jds.2017.08.001
Abstract: Background/purpose Langerhans cells (LCs) are antigen-presenting cells. This study assessed the LC counts in 80 dentigerous cysts (DCs). Materials and methods The S100-positive LC numbers in the lining epithelia and subepithelial connective tissues were counted… read more here.
Keywords: lining epithelia; hpf respectively; inflammation; cells hpf ... See more keywords
A Liposomal Platform for Delivery of a Protein Antigen to Langerin-Expressing Cells
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b00402
Abstract: The skin is an attractive site for vaccination and harbors a dense network of Langerhans cells that are the prime target for antigen delivery approaches in the epidermis. While specific targeting of Langerhans cells has… read more here.
Keywords: protein; delivery; langerin; antigen ... See more keywords
Preparation of Polymeric Films of PVDMA–PEI Functionalized with Fatty Acids for Studying the Adherence and Proliferation of Langerhans β-Cells
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.9b04313
Abstract: This study reports the synthesis of thin polymeric films by the layer-by-layer deposition and covalent cross-linking of polyvinyl dimethylazlactone and polyethylene imine, which were functionalized with lauric (12-C), myristic (14-C), and palmitic (16-C) saturated fatty… read more here.
Keywords: microscopy; fatty acids; polymeric films; proliferation langerhans ... See more keywords
Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Immunology"
DOI: 10.1038/cmi.2015.87
Abstract: The potential of the skin immune system to generate immune responses is well established, and the skin is actively exploited as a vaccination site. Human skin contains several antigen-presenting cell subsets with specialized functions. In… read more here.
Keywords: mediated internalization; human langerhans; cross; early endosomes ... See more keywords
Ontogeny and function of murine epidermal Langerhans cells
Sign Up to like & getrecommendations! Published in 2017 at "Nature Immunology"
DOI: 10.1038/ni.3815
Abstract: Langerhans cells (LCs) are epidermis-resident antigen-presenting cells that share a common ontogeny with macrophages but function as dendritic cells (DCs). Their development, recruitment and retention in the epidermis is orchestrated by interactions with keratinocytes through… read more here.
Keywords: ontogeny function; murine epidermal; function murine; immunology ... See more keywords
Early antitumor activity of oral Langerhans cells is compromised by a carcinogen
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2118424119
Abstract: Significance Oral cancer is often diagnosed at late stages, resulting in a poor prognosis of this disease. Understanding early carcinogenic events taking place during the development of oral cancer is, therefore, an important unmet clinical… read more here.
Keywords: carcinogen; langerhans cells; oral cancer; compromised carcinogen ... See more keywords
Langerhans cells and SFRP2/Wnt/beta‐catenin signalling control adaptation of skin epidermis to mechanical stretching
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17111
Abstract: Skin can be mechanically stimulated to grow through a clinical procedure called tissue expansion (TE). Using a porcine TE model, we determined that expansion promptly activates transcription of SFRP2 in skin and we revealed that… read more here.
Keywords: langerhans cells; wnt beta; catenin signalling; cells sfrp2 ... See more keywords
Human Herpesvirus 8 Infects and Replicates in Langerhans Cells and Interstitial Dermal Dendritic Cells and Impairs Their Function
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.00909-17
Abstract: ABSTRACT The predominant types of dendritic cells (DC) in the skin and mucosa are Langerhans cells (LC) and interstitial dermal DC (iDDC). LC and iDDC process cutaneous antigens and migrate out of the skin and… read more here.
Keywords: interstitial dermal; infection; dendritic cells; hhv ... See more keywords
Langerhans Cells, T Cells, and B Cells in Oral Lichen Planus and Oral Leukoplakia
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Dentistry"
DOI: 10.1155/2022/5430309
Abstract: Although oral lichen planus (OLP) and oral leukoplakia (LPL) have different pathogenetic profiles, both may involve chronic inflammation. The aim of this observational study was to evaluate the inflammatory cell profiles of OLP and LPL.… read more here.
Keywords: langerhans cells; oral lichen; lichen planus; oral leukoplakia ... See more keywords