Divergent Evolution of Lanthipeptide Stereochemistry
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DOI: 10.1021/acschembio.2c00492
Abstract: The three-dimensional structure of natural products is critical for their biological activities and, as such, enzymes have evolved that specifically generate active stereoisomers. Lanthipeptides are post-translationally modified peptidic natural products that contain macrocyclic thioethers featuring… read more here.
Keywords: evolution lanthipeptide; divergent evolution; melan; lanthipeptide stereochemistry ... See more keywords