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Published in 2022 at "ACS Chemical Biology"
DOI: 10.1021/acschembio.2c00492
Abstract: The three-dimensional structure of natural products is critical for their biological activities and, as such, enzymes have evolved that specifically generate active stereoisomers. Lanthipeptides are post-translationally modified peptidic natural products that contain macrocyclic thioethers featuring…
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Keywords:
evolution lanthipeptide;
divergent evolution;
melan;
lanthipeptide stereochemistry ... See more keywords