Linking a nuclear lncRNA to cytoplasmic lysosome integrity and cell death
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123082119
Abstract: Long noncoding RNAs (lncRNAs) are noncoding RNAs that are ≥200 nucleotides in size and may function in diverse biological processes (1). Although the human genome may encode up to ∼100,000 lncRNAs, most lncRNAs are at… read more here.
Keywords: cell death; cell; laptm5; expression ... See more keywords
LAPTM5 protein can regulate TGF-β mediated MAPK and smad signaling pathways in ovarian cancer cell
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DOI: 10.1093/annonc/mdz238.029
Abstract: Abstract Background LAPTM5 (lysosomal-associated protein transmembrane 5) is a protein that is preferentially expressed in immune cells, and it interacts with the Nedd4 family of ubiquitin ligases. Recent studies in T and B cells identified… read more here.
Keywords: laptm5; signaling pathways; smad signaling; ovarian cancer ... See more keywords
Key Prognostic Value of Lysosomal Protein Transmembrane 5 in Kidney Renal Clear Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s357013
Abstract: Objective To investigate the significance of lysosomal protein transmembrane 5 (LAPTM5) in kidney renal clear cell carcinoma (KIRC). Methods Bioinformatics analysis as an efficient and accurate method was employed to explore the expression levels, prognostic… read more here.
Keywords: kirc patients; laptm5; lysosomal protein; kidney renal ... See more keywords