Safety and preliminary efficacy of argatroban plus dual antiplatelet therapy for acute mild to moderate ischemic stroke with large artery atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2664
Abstract: Previous studies suggest the benefit of dual antiplatelet therapy (DAPT) for acute ischemic stroke with large artery atherosclerosis (LAA) etiology, but there is no study about the effect of DAPT plus anticoagulant in this population. read more here.
Keywords: large artery; antiplatelet therapy; artery atherosclerosis; dual antiplatelet ... See more keywords
Thromboxane A synthase 1 gene expression and promotor haplotypes are associated with risk of large artery‐atherosclerosis stroke in Iranian population
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28787
Abstract: Large artery atherosclerosis (LAA) is known as an important cause of ischemic stroke (IS), which is a multifactorial disorder. Many candidate genes have been proposed for IS like (TBXAS1) that plays a significant role in… read more here.
Keywords: atherosclerosis stroke; large artery; artery atherosclerosis; tbxas1 ... See more keywords
Selenium and large artery structure and function: a 10-year prospective study
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Nutrition"
DOI: 10.1007/s00394-018-1875-y
Abstract: PurposeDespite selenium’s beneficial effects in counteracting oxidative stress, inflammation, and vascular endothelial dysfunction, controversial results exist regarding the long-term associations between selenium and atherosclerosis, arterial stiffness, and hypertension. We investigated in normal and selenium-deficient groups… read more here.
Keywords: large artery; artery structure; blood pressure; selenium ... See more keywords
Large-Artery Stiffness in Health and Disease: JACC State-of-the-Art Review.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2019.07.012
Abstract: A healthy aorta exerts a powerful cushioning function, which limits arterial pulsatility and protects the microvasculature from potentially harmful fluctuations in pressure and blood flow. Large-artery (aortic) stiffening, which occurs with aging and various pathologic… read more here.
Keywords: artery stiffness; large artery; arterial stiffness; stiffness health ... See more keywords
Sleep Apnea Syndrome And Large Artery Subclinical Damage: Targeting Thoracic Aortic Dilatation.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of hypertension"
DOI: 10.1093/ajh/hpac006
Abstract: AIM Whether obstructive sleep apnea (OSA) actually represents an independent risk factor for aortic dilation in the general population is unclear. We investigated this issue through a review and a meta-analysis of cardiac imaging studies… read more here.
Keywords: damage; syndrome large; large artery; sleep apnea ... See more keywords
Lipoprotein(a) is associated with large artery atherosclerosis stroke aetiology and stroke recurrence among patients below the age of 60 years: results from the BIOSIGNAL study.
Sign Up to like & getrecommendations! Published in 2021 at "European heart journal"
DOI: 10.1093/eurheartj/ehab081
Abstract: AIMS Lipoprotein(a) [Lp(a)] is a recognized causal risk factor for atherosclerotic cardiovascular disease but its role for acute ischaemic stroke (AIS) is controversial. In this study, we evaluated the association of Lp(a) with large artery… read more here.
Keywords: large artery; artery atherosclerosis; study; stroke aetiology ... See more keywords
Serum YKL‐40, a prognostic marker in patients with large‐artery atherosclerotic stroke
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurologica Scandinavica"
DOI: 10.1111/ane.12688
Abstract: Inflammation comprises important aspects of large‐artery atherosclerosis (LAA) stroke pathophysiology. YKL‐40 is a new and emerging biomarker that is associated with both acute and chronic inflammations. Elevated serum concentrations of YKL‐40 have been reported in… read more here.
Keywords: large artery; serum ykl; ykl prognostic; stroke ... See more keywords
Magnitude of blood pressure change and clinical outcomes after thrombectomy in stroke caused by large artery occlusion
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DOI: 10.1111/ene.14807
Abstract: Extremes of both high and low systolic blood pressure (SBP) after mechanical thrombectomy (MT) in large artery occlusion stroke are known predictors of unfavorable outcome. However, the effect of SBP change (∆SBP) during the first… read more here.
Keywords: large artery; artery occlusion; blood pressure;
The Charlotte large artery occlusion endovascular therapy outcome score predicts outcome after basilar artery thrombectomy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroimaging"
DOI: 10.1111/jon.13039
Abstract: The Charlotte Large artery occlusion Endovascular therapy Outcome Score (CLEOS) and Totaled Health Risks in Vascular Events (THRIVE) predict functional outcomes after anterior circulation endovascular thrombectomy (EVT). We evaluated the performance of CLEOS and THRIVE… read more here.
Keywords: large artery; artery; occlusion endovascular; charlotte large ... See more keywords
E-041 Early recanalization rate after iv-tpa and treatment results of additional intra-arterial thrombolysis in large artery intracranial occlusion disease patients
Sign Up to like & getrecommendations! Published in 2017 at "Journal of NeuroInterventional Surgery"
DOI: 10.1136/neurintsurg-2017-snis.113
Abstract: Background and objective Intravenous tissue plasminogen activator administration (IV-tPA) is the only standard treatment for acute ischemic stroke patients, but its therapeutic effect on in large artery intracranial occlusive disease (LAICOD) is questionable. We attempted… read more here.
Keywords: large artery; rate; recanalization rate; rate tpa ... See more keywords
Thrombosis origin identification of cardioembolism and large artery atherosclerosis by distinct metabolites
Sign Up to like & getrecommendations! Published in 2022 at "Journal of NeuroInterventional Surgery"
DOI: 10.1136/neurintsurg-2022-019047
Abstract: Background The diagnosis of cerebral thrombosis origin is challenging and remains unclear. This study aims to identify thrombosis due to cardioembolism (CE) and large artery atherosclerosis (LAA) from a new perspective of distinct metabolites. Methods… read more here.
Keywords: cardioembolism large; distinct metabolites; artery atherosclerosis; thrombosis origin ... See more keywords