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1
Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.01014
Abstract: Homologous to the E6AP carboxyl terminus (HECT) and regulator of chromosome condensation 1 (RCC1)-like domain-containing proteins (HERCs) belong to the superfamily of ubiquitin ligases. HERC proteins are divided into two subfamilies, Large and Small HERCs.…
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Keywords:
functional relevance;
hercing structural;
large herc;
ubiquitin ligases ... See more keywords
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2
Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054906
Abstract: Protein ubiquitylation acts as a complex cell signaling mechanism since the formation of different mono- and polyubiquitin chains determines the substrate’s fate in the cell. E3 ligases define the specificity of this reaction by catalyzing…
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Keywords:
mapk signaling;
ubiquitin ligases;
large herc;
signaling pathways ... See more keywords