Cell membrane-anchored and tumor-targeted IL-12 (attIL12)-T cell therapy for eliminating large and heterogeneous solid tumors
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DOI: 10.1136/jitc-2021-003633
Abstract: Background Adoptive T-cell transfer has become an attractive therapeutic approach for hematological malignancies but shows poor activity against large and heterogeneous solid tumors. Interleukin-12 (IL-12) exhibits potent antitumor efficacy against solid tumors, but its clinical… read more here.
Keywords: cell; large heterogeneous; cell membrane; solid tumors ... See more keywords