LncRNA TTN‐AS1/miR‐134‐5p/PAK3 axis regulates the radiosensitivity of human large intestine cancer cells through the P21 pathway and AKT/GSK‐3β/β‐catenin pathway
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biology International"
DOI: 10.1002/cbin.11436
Abstract: Radiotherapy is an important adjuvant treatment for large intestine cancer even though it does not cause any response in many patients. The present study aimed to investigate the effects of the TTN antisense RNA 1… read more here.
Keywords: ttn as1; intestine cancer; cancer cells; cancer ... See more keywords
Characterisation of the bacterial community in the gastrointestinal tracts of elk (Cervus canadensis)
Sign Up to like & getrecommendations! Published in 2018 at "Antonie van Leeuwenhoek"
DOI: 10.1007/s10482-018-1150-5
Abstract: The resident bacteria of the gastrointestinal tract (GIT) and the behaviour of these microbes have been poorly characterised in elk as compared to other ruminant animal species such as sheep and cattle. In addition, most… read more here.
Keywords: community; cervus canadensis; elk cervus; bacterial community ... See more keywords
An epidemiologic perspective on the stem cell hypothesis in human carcinogenesis.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer epidemiology"
DOI: 10.1016/j.canep.2017.09.001
Abstract: BACKGROUND Tomasetti and Vogelstein have hypothesized that the patterns of cancer incidence in various cells and tissues are highly correlated with the estimated lifetime number of stem cell divisions. The authors reviewed the risks in… read more here.
Keywords: cancer; stem cell; epidemiologic perspective; large intestine ... See more keywords
Akkermansia muciniphila fermentation culture based on a novel bionic large intestine dynamic digestion model
Sign Up to like & getrecommendations! Published in 2021 at "Food bioscience"
DOI: 10.1016/j.fbio.2021.101260
Abstract: Abstract Akkermansia muciniphila, a member of the human intestinal microflora, is a potential next-generation probiotic. Therefore, the optimization of in vitro culture conditions for A. muciniphila is a promising research direction. In this study, an… read more here.
Keywords: large intestine; muciniphila; intestine dynamic; bionic large ... See more keywords
Reduced infant rhesus macaque growth rates due to environmental enteric dysfunction and association with histopathology in the large intestine
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-021-27925-x
Abstract: Environmental enteric dysfunction is associated with malnutrition as well as infant growth stunting and has been classically defined by villous blunting, decreased crypt-to-villus ratio, and inflammation in the small intestine. Here, we characterized environmental enteric… read more here.
Keywords: enteric dysfunction; histopathology; large intestine; environmental enteric ... See more keywords
Influence of different inclusion levels and chain length of inulin on microbial ecology and the state of mucosal protective barrier in the large intestine of young pigs
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DOI: 10.1071/an16014
Abstract: The objective of the study was to examine the effect of inulin level, in regard to its degree of polymerisation (DP), on microbial activity and mucosal immune system of the large intestine of pigs. A… read more here.
Keywords: colon; mucosal; level; large intestine ... See more keywords
Cellulolytic bacteria in the large intestine of mammals
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2031694
Abstract: ABSTRACT The utilization of dietary cellulose by resident bacteria in the large intestine of mammals, both herbivores and omnivores (including humans), has been a subject of interest since the nineteenth century. Cellulolytic bacteria are key… read more here.
Keywords: large intestine; intestine mammals; cellulolytic bacteria; host ... See more keywords
Regulation of Chlamydia spreading from the small intestine to the large intestine via an immunological barrier
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DOI: 10.1111/imcb.12446
Abstract: The obligate intracellular bacterium Chlamydia is a genital tract pathogen that can also colonize the gastrointestinal tract for long periods. The long‐lasting colonization is dependent on chlamydial spreading from the small intestine to the large… read more here.
Keywords: barrier; intestinal barrier; small intestine; chlamydia ... See more keywords
The Lumenal Microbiota Varies Biogeographically in the Gastrointestinal Tract of Rhesus Macaques
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DOI: 10.1128/spectrum.00343-22
Abstract: For the study of upper gastrointestinal microbiota in humans, endoscopic sampling is the main source of information, which limits the understanding of healthy upper gastrointestinal microbiota. Rhesus monkeys show very close similarity to humans in… read more here.
Keywords: gastrointestinal microbiota; small intestine; large intestine; intestine ... See more keywords
Microvesicular hyperplastic polyp and sessile serrated lesion of the large intestine: a biological continuum or separate entities?
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Pathology"
DOI: 10.1136/jcp-2023-208783
Abstract: The range of lesions with a serrated appearance within the large intestine has expanded and become more complex over the last 30 years. The majority of these were previously known as metaplastic polyps but are… read more here.
Keywords: large intestine; serrated lesion; goblet cell; separate entities ... See more keywords
Modeling and analysis of the Delta-Notch dependent boundary formation in the Drosophila large intestine
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DOI: 10.1186/s12918-017-0455-8
Abstract: BackgroundThe boundary formation in the Drosophila large intestine is widely studied as an important biological problem. It has been shown that the Delta-Notch signaling pathway plays an essential role in the formation of boundary cells.ResultsIn… read more here.
Keywords: formation; formation drosophila; delta notch; large intestine ... See more keywords