Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate
Sign Up to like & getrecommendations! Published in 2018 at "Protein & Cell"
DOI: 10.1007/s13238-018-0526-7
Abstract: Assembly of eukaryotic ribosome is a complicated and dynamic process that involves a series of intermediates. It is unknown how the highly intertwined structure of 60S large ribosomal subunits is established. Here, we report the… read more here.
Keywords: structure early; large ribosomal; half assembled; structure ... See more keywords
Accretion history of large ribosomal subunits deduced from theoretical minimal RNA rings is congruent with histories derived from phylogenetic and structural methods.
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DOI: 10.1016/j.gene.2020.144436
Abstract: Accretions of tRNAs presumably formed the large complex ribosomal RNA structures. Similarities of tRNA secondary structures with rRNA secondary structures increase with the integration order of their cognate amino acid in the genetic code, indicating… read more here.
Keywords: rna rings; secondary structures; rna; large ribosomal ... See more keywords
The Npa1p complex chaperones the assembly of the earliest eukaryotic large ribosomal subunit precursor
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DOI: 10.1371/journal.pgen.1007597
Abstract: The early steps of the production of the large ribosomal subunit are probably the least understood stages of eukaryotic ribosome biogenesis. The first specific precursor to the yeast large ribosomal subunit, the first pre-60S particle,… read more here.
Keywords: pre ribosomal; ribosomal subunit; large ribosomal; 25s rrna ... See more keywords