The transient expression of CHIKV VLP in large stirred tank bioreactors
Sign Up to like & getrecommendations! Published in 2019 at "Cytotechnology"
DOI: 10.1007/s10616-019-00346-x
Abstract: Transient gene expression (TGE) bioprocesses have been difficult to scale up in large stirred tank bioreactors with volumes of more than 1.5 L. Low production levels are often observed, but the causes have not been… read more here.
Keywords: stirred tank; transient expression; tank bioreactors; large stirred ... See more keywords
Compartmental modeling of large stirred tank bioreactors with high gas volume fractions
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2017.11.182
Abstract: Abstract Manufacturing processes in bioreactors are initially developed at small scales. These are usually operated in homogeneous regime. However, the flow regime may go through transition during scale-up to production size and become heterogeneous. Measurements… read more here.
Keywords: volume; mass transfer; compartmental modeling; gas ... See more keywords