Functional and Safety Outcomes of Carotid Artery Stenting and Mechanical Thrombectomy for Large Vessel Occlusion Ischemic Stroke With Tandem Lesions
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DOI: 10.1001/jamanetworkopen.2023.0736
Abstract: Key Points Question Is carotid artery stenting (CAS) during mechanical thrombectomy (MT) associated with improved functional outcome without an increase in hemorrhagic rates in patients with large vessel occlusion ischemic stroke with tandem lesions, defined… read more here.
Keywords: large vessel; tandem lesions; occlusion; carotid artery ... See more keywords
Thrombectomy With the pRESET vs Solitaire Stent Retrievers as First-Line Large Vessel Occlusion Stroke Treatment
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DOI: 10.1001/jamaneurol.2023.5010
Abstract: Key Points Question Among patients with large vessel occlusion (LVO) stroke, does thrombectomy with the pRESET device restore flow and reduce disability similarly to the Solitaire device? Findings In this randomized clinical trial including 340… read more here.
Keywords: vessel occlusion; preset; solitaire; large vessel ... See more keywords
Intra-Arterial Tenecteplase After Successful Reperfusion in Large Vessel Occlusion Stroke
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2025.2036
Abstract: This phase 1 and 2 randomized clinical trial investigated both the safety threshold and efficacy of 3 different doses of tenecteplase when given by catheter to patients with large vessel occlusion stroke after successful endovascular… read more here.
Keywords: vessel occlusion; occlusion stroke; tenecteplase; large vessel ... See more keywords
Optimal Head-of-Bed Positioning Before Thrombectomy in Large Vessel Occlusion Stroke
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DOI: 10.1001/jamaneurol.2025.2253
Abstract: This randomized clinical trial investigates if use of a 0° head position is superior to a 30° head position for maintaining clinical stability in individuals with large vessel occlusion stroke who are candidates for thrombectomy… read more here.
Keywords: large vessel; vessel occlusion; occlusion stroke; optimal head ... See more keywords
Hyperacute immune responses associate with immediate neuropathology and motor dysfunction in large vessel occlusions
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51719
Abstract: Despite successful endovascular therapy, a proportion of stroke patients exhibit long‐term functional decline, regardless of the cortical reperfusion. Our objective was to evaluate the early activation of the adaptive immune response and its impact on… read more here.
Keywords: large vessel; immediate neuropathology; responses associate; immune responses ... See more keywords
Intravenous thrombolysis prior to mechanical thrombectomy in large vessel occlusions
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Neurology"
DOI: 10.1002/ana.25544
Abstract: The substantial clinical improvement in acute ischemic stroke (AIS) patients treated with mechanical thrombectomy (MT), combined with the poor response of proximal intracranial occlusions to intravenous thrombolysis (IVT), led to questions regarding the utility of… read more here.
Keywords: mechanical thrombectomy; occlusions intravenous; large vessel; intravenous thrombolysis ... See more keywords
Thrombectomy versus Medical Management in Mild Strokes due to Large Vessel Occlusion: Exploratory Analysis from the EXTEND‐IA Trials and a Pooled International Cohort
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26418
Abstract: This study was undertaken to evaluate functional and safety outcomes for endovascular thrombectomy (EVT) versus medical management (MM) in patients with large vessel occlusion (LVO) and mild neurological deficits, stratified by perfusion imaging mismatch. read more here.
Keywords: vessel occlusion; large vessel; medical management; versus medical ... See more keywords
White matter hyperintensities had a correlation with the cerebral perfusion level, but no correlation with the severity of large vessel stenosis in the anterior circulation
Sign Up to like & getrecommendations! Published in 2023 at "Brain and Behavior"
DOI: 10.1002/brb3.2932
Abstract: The contribution of large vessel stenosis to the development of white matter hyperintensities (WMHs) has not been fully elucidated. This study aims to explore the correlation between ipsilateral white matter hyperintensities (WMHs) and the severity… read more here.
Keywords: white matter; matter hyperintensities; large vessel; vessel stenosis ... See more keywords
Development of a Diagnostic Prediction Model for Post‐Stroke Cognitive Impairment in Acute Large Vessel Occlusion Stroke Using Multimodal MRI and PET/CT: A Study Protocol
Sign Up to like & getrecommendations! Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70613
Abstract: Stroke is a leading cause of morbidity and disability worldwide. Post‐stroke cognitive impairment (PSCI) significantly affects long‐term prognosis in acute anterior circulation large‐vessel occlusion stroke (LVO‐AIS). This study aims to develop a PSCI prediction model… read more here.
Keywords: cognitive impairment; post stroke; vessel occlusion; stroke cognitive ... See more keywords
A Meta‐Analysis of the Association Between Early Venous Filling and Hemorrhagic Transformation After Endovascular Treatment in Acute Large Vessel Occlusion
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DOI: 10.1002/brb3.70663
Abstract: This meta‐analysis assessed the link between early venous filling (EVF) and hemorrhagic transformation (HT) post‐endovascular treatment (EVT) in acute ischemic stroke (AIS) patients with large vessel occlusion (LVO). read more here.
Keywords: meta analysis; venous filling; large vessel; early venous ... See more keywords
An alternative treatment strategy for large vessel coronary perforations
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DOI: 10.1002/ccd.28034
Abstract: The standard treatment for large vessel coronary perforations is implantation of a covered stent. Antegrade attempts for crossing a right coronary artery chronic total occlusion resulted in guidewire and microcatheter exit with pericardial bleeding. A… read more here.
Keywords: treatment; treatment strategy; large vessel; alternative treatment ... See more keywords