A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43
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DOI: 10.1126/sciadv.abm6376
Abstract: A number of neurodegenerative conditions are associated with the formation of cytosolic inclusions of TDP-43 within neurons. We expressed full-length TDP-43 in a motoneuron/neuroblastoma hybrid cell line (NSC-34) and exploited the high-resolution power of stimulated… read more here.
Keywords: quantitative biology; biology approach; inclusions tdp; microscopy ... See more keywords