Articles with "larotrectinib using" as a keyword



Metabolic Stability Assessment of Larotrectinib Using Liquid Chromatography Tandem Mass Spectrometry

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Published in 2020 at "Drug Design, Development and Therapy"

DOI: 10.2147/dddt.s235934

Abstract: Introduction Larotrectinib (VITRAKVI) is an orally potent tropomyosin receptor kinase (Trk) inhibitor that acts by competitive inhibition of all corresponding receptor kinases. It demonstrated a marked response rate (75%) and robust anticancer activity in Trk… read more here.

Keywords: metabolic stability; larotrectinib using; assessment larotrectinib; stability ... See more keywords