Radiotherapy vs surgery for T1‐2N0M0 laryngeal squamous cell carcinoma: A population‐based and propensity score matching study
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1525
Abstract: There are conflicting reports about whether radiotherapy or surgery is optimal for early‐stage laryngeal squamous cell carcinoma (LSCC), although both have recently been recommended. Patients with T1‐2N0M0 LSCC in the population‐based SEER database who underwent… read more here.
Keywords: surgery; cell carcinoma; squamous cell; radiotherapy surgery ... See more keywords
USP39 Depletion Plays Repressive Roles in Laryngeal Squamous Cell Carcinoma Development
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DOI: 10.1002/cbin.70035
Abstract: Laryngeal squamous cell carcinoma (LSCC) is a prevalent malignant tumor of the upper respiratory tract. Ubiquitin‐specific protease 39 (USP39) has been identified as an oncogenic regulator in various malignant tumors; however, its specific roles in… read more here.
Keywords: depletion; cell; squamous cell; cell carcinoma ... See more keywords
Chemotherapy alone for stage II–IVa laryngeal squamous cell carcinoma: A 20‐year follow‐up
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DOI: 10.1002/cncr.70177
Abstract: Current treatment options for nonmetastatic laryngeal squamous cell carcinoma include radiotherapy, chemoradiotherapy, and surgery, which can result in significant morbidity. This study reports the 20‐year outcomes of a single‐modality chemotherapy as a larynx preservation strategy… read more here.
Keywords: cell carcinoma; laryngeal squamous; squamous cell; stage iva ... See more keywords
Upstream transcription factor 1 suppresses laryngeal squamous cell carcinoma progression through transcriptional activation of junctional adhesion molecule 3
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DOI: 10.1002/iub.70013
Abstract: Laryngeal squamous cell carcinoma (LSCC) exhibits aggressive growth, frequent recurrence, and a notable resistance to existing treatments. Building upon prior discoveries that identified junctional adhesion molecule 3 (JAM3) as a critical tumor suppressor in LSCC,… read more here.
Keywords: squamous cell; adhesion molecule; cell carcinoma; laryngeal squamous ... See more keywords
Tumor suppression effect of targeting periostin with siRNA in a nude mouse model of human laryngeal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22622
Abstract: The incidence of laryngeal carcinoma is increasing, however, the mechanism is not fully understood. We aimed to investigate the efficacy of periostin gene silencing by siRNA on tumor inhibition, in a novel nude mouse model… read more here.
Keywords: nude mouse; laryngeal squamous; carcinoma; human laryngeal ... See more keywords
tRNAIni CAT inhibits proliferation and promotes apoptosis of laryngeal squamous cell carcinoma cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23821
Abstract: Laryngeal squamous cell carcinoma (LSCC) brings a heavy blow to the patient's voice. Transfer RNA (tRNA) is a common RNA, the roles of tRNAs in LSCC are largely unknown. read more here.
Keywords: squamous cell; trnaini cat; cell carcinoma; laryngeal squamous ... See more keywords
A prognostic nomogram for predicting risk of recurrence in laryngeal squamous cell carcinoma patients after tumor resection to assist decision making for postoperative adjuvant treatment
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25614
Abstract: This study aimed to create a nomogram for postoperative prediction of the risk of recurrence in laryngeal squamous cell carcinoma patients who received laryngectomy alone and to assess indications for postoperative adjuvant treatments (POAT). read more here.
Keywords: cell carcinoma; squamous cell; risk recurrence; carcinoma patients ... See more keywords
Treatment and outcome among patients with laryngeal squamous cell carcinoma in Stockholm—A population‐based study
Sign Up to like & getrecommendations! Published in 2023 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.1034
Abstract: Survival of patients with advanced laryngeal squamous cell carcinoma (LSCC) remains poor and management protocols warrant further development. We thus investigated treatment and outcome‐related factors for LSCC in Stockholm, Sweden. read more here.
Keywords: cell carcinoma; squamous cell; treatment outcome; laryngeal squamous ... See more keywords
CircBFAR correlates with poor prognosis and promotes laryngeal squamous cell cancer progression through miR‐31‐5p/COL5A1 axis
Sign Up to like & getrecommendations! Published in 2022 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.966
Abstract: Laryngeal squamous cell cancer (LSCC) is a highly malignant tumor originating from the respiratory system. Circular RNAs have been reported to be associated with the treatment and prognosis of a variety of cancers, including LSCC. read more here.
Keywords: cell cancer; squamous cell; prognosis; laryngeal squamous ... See more keywords
Identification of miR‐145‐5p‐Centered Competing Endogenous RNA Network in Laryngeal Squamous Cell Carcinoma
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DOI: 10.1002/pmic.201900020
Abstract: This study intends to investigate the transcriptional regulatory role of miR‐145‐5p in laryngeal squamous cell carcinoma (LSCC). LSCC cell line TU‐177 is transfected with miR‐145‐5p mimics, generating miR‐145‐5p‐overexpression LSCC cells. Whole transcriptome microarrays are used… read more here.
Keywords: cell; mir 145; cell carcinoma; squamous cell ... See more keywords
Autophagy suppression enhances DNA damage and cell death upon treatment with PARP inhibitor Niraparib in laryngeal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-019-10148-y
Abstract: Although poly (ADP-ribose) polymerase (PARP) inhibitors, as anti-tumor drugs targeting the DNA damage response (DDR), have been used for the therapy of various tumors, few researches reported their effect on laryngeal squamous cell carcinoma (LSCC).… read more here.
Keywords: dna damage; cell; cell carcinoma; squamous cell ... See more keywords