Articles with "laser desorption" as a keyword



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Aptamer-Functionalized Fractal Nanoplasmonics-Assisted Laser Desorption/Ionization Mass Spectrometry for Metabolite Detection.

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Published in 2022 at "ChemPlusChem"

DOI: 10.1002/cplu.202100479

Abstract: Accurate profiling of metabolites in biofluids provides a feasible approach to disease diagnosis and therapeutic evaluation in clinics. However, current material-based analytical platforms for in vitro metabolite detection often requires tedious sample pretreatment. To address this… read more here.

Keywords: functionalized fractal; assisted laser; laser desorption; desorption ionization ... See more keywords
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Rapid antibody conformational screening by matrix assisted laser desorption ionization hydrogen-deuterium exchange mass spectrometry.

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Published in 2022 at "Journal of separation science"

DOI: 10.1002/jssc.202100986

Abstract: Recent advances in the field of cancer biology have accelerated the discovery and development of novel biopharmaceuticals. At the forefront of these drug development efforts are high-throughput screening, compressed timelines and limited sample quantities, all… read more here.

Keywords: assisted laser; laser desorption; desorption ionization; hydrogen deuterium ... See more keywords
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Matrix‐assisted laser desorption/ionization mass spectrometry biotyping, an approach for deciphering and assessing the identity of the honeybee pathogen Nosema

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Published in 2020 at "Rapid Communications in Mass Spectrometry"

DOI: 10.1002/rcm.8980

Abstract: Rationale The microsporidia are obligate intracellular pathogenic fungi that parasitize a wide range of invertebrate and vertebrate hosts and have important impacts on health, food security and the economy. In this paper, we focus on… read more here.

Keywords: matrix assisted; laser desorption; mass spectrometry; mass ... See more keywords
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Mass Spectrometry Imaging of Biological Tissues by Laser Desorption Ionization from Silicon Nanopost Arrays.

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Published in 2022 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-2030-4_6

Abstract: Mass spectrometry imaging (MSI) plays an expanding role in the label-free spatial mapping of hundreds of molecules simultaneously. Currently, matrix-assisted laser desorption ionization (MALDI) is among the most widely adopted MSI techniques. However, matrix application… read more here.

Keywords: laser desorption; mass spectrometry; ionization; spectrometry imaging ... See more keywords
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Applications of Matrix-Assisted Laser Desorption Ionization In-Source Decay Mass Spectrometry.

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Published in 2019 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-030-15950-4_3

Abstract: Matrix-Assisted Laser Desorption Ionization In-Source Decay (MALDI-ISD) Mass Spectrometry is a very powerful tool for providing terminal sequence information of biomolecules with minimal sample preparations. Fragmentation is induced at the position where hydrogen radical transfers… read more here.

Keywords: ionization source; assisted laser; laser desorption; maldi isd ... See more keywords
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Surface tuning laser desorption/ionization mass spectrometry (STLDI-MS) for the analysis of small molecules using quantum dots

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Published in 2017 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-017-0433-4

Abstract: In most applications of quantum dots (QDs) for surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS), one side of QDs is supported by a solid substrate (stainless - steel plate), whereas the other side is in contact… read more here.

Keywords: mass spectrometry; ionization mass; laser desorption; ionization ... See more keywords
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Recent applications of metal–organic frameworks in matrix-assisted laser desorption/ionization mass spectrometry

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Published in 2019 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-019-01876-1

Abstract: Metal–organic frameworks (MOFs) have drawn great interest in recent decades due to their fascinating structures, unusual physical properties, versatile modification strategies, and biological compatibilities. In this review, we describe recent progress in the application of… read more here.

Keywords: metal organic; assisted laser; laser desorption; organic frameworks ... See more keywords
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Identification to species level of live single microalgal cells from plankton samples with matrix-free laser/desorption ionization mass spectrometry

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Published in 2020 at "Metabolomics"

DOI: 10.1007/s11306-020-1646-7

Abstract: Introduction Marine planktonic communities are complex microbial consortia often dominated by microscopic algae. The taxonomic identification of individual phytoplankton cells usually relies on their morphology and demands expert knowledge. Recently, a live single-cell mass spectrometry… read more here.

Keywords: laser desorption; mass spectrometry; mass; identification ... See more keywords
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The Characterization of Laser Ablation Patterns and a New Definition of Resolution in Matrix Assisted Laser Desorption Ionization Imaging Mass Spectrometry (MALDI-IMS)

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Published in 2017 at "Journal of The American Society for Mass Spectrometry"

DOI: 10.1007/s13361-017-1632-0

Abstract: AbstractMatrix assisted laser desorption ionization imaging mass spectrometry (MALDI-IMS) is a technique that has seen a sharp rise in both use and development. Despite this rapid adoption, there have been few thorough investigations into the… read more here.

Keywords: resolution; mass spectrometry; mass; assisted laser ... See more keywords
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A Simple Sonication Improves Protein Signal in Matrix-Assisted Laser Desorption Ionization Imaging

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Published in 2018 at "Journal of The American Society for Mass Spectrometry"

DOI: 10.1007/s13361-018-1889-y

Abstract: AbstractProper matrix application is crucial in obtaining high quality matrix-assisted laser desorption ionization (MALDI) mass spectrometry imaging (MSI). Solvent-free sublimation was essentially introduced as an approach of homogeneous coating that gives small crystal size of… read more here.

Keywords: matrix; sonication; assisted laser; laser desorption ... See more keywords
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Soft Matrix–Assisted Laser Desorption/Ionization for Labile Glycoconjugates

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Published in 2019 at "Journal of The American Society for Mass Spectrometry"

DOI: 10.1007/s13361-019-02208-4

Abstract: AbstractSince its introduction, matrix-assisted laser desorption/ionization (MALDI) has been widely used for the mass analysis of biomolecules. The “soft ionization” of MALDI enables accurate mass determination of intact biomolecules. However, the ionization and desorption processes… read more here.

Keywords: desorption; assisted laser; ionization; laser desorption ... See more keywords