Up-regulated microRNA-218-5p ameliorates the damage of dopaminergic neurons in rats with Parkinson’s disease via suppression of LASP1
Sign Up to like & getrecommendations! Published in 2021 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2020.10.019
Abstract: OBJECTIVE Parkinson's disease (PD) is a frequent degenerative disease of the nervous system with undefined pathogenesis. This study explored the protective effect of microRNA (miR)-218-5p on dopaminergic neuron injury in substantia nigra (SN) of rats… read more here.
Keywords: mir 218; disease; neurons rats; lasp1 ... See more keywords
Endometrial stromal cell proteomic analysis reveals LIM and SH3 protein 1 (LASP1) plays important roles in the progression of adenomyosis.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular human reproduction"
DOI: 10.1093/molehr/gaab008
Abstract: Adenomyosis is one of the most common gynecological disorders that the molecular events underlying its pathogenesis remain not fully understood. Prior studies have shown that endometrial stromal cells (ESCs) played crucial roles in the pathogenesis… read more here.
Keywords: protein; adenomyosis; endometrial stromal; lim sh3 ... See more keywords
Long non-coding RNA MIAT promotes papillary thyroid cancer progression through upregulating LASP1
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Cell International"
DOI: 10.1186/s12935-019-0913-z
Abstract: BackgroundAccumulating evidences indicate that long non-coding RNAs (lncRNAs) play an important role in initiation and development of thyroid cancer. However, the underlying molecular mechanism remains elusive.MethodsTo explore potential oncogenic and tumor suppressive lncRNAs in papillary… read more here.
Keywords: ptc; miat; thyroid cancer; lasp1 ... See more keywords
lncRNA MAFG-AS1 Contributes to Esophageal Squamous-Cell Carcinoma Progression via Regulating miR143/LASP1
Sign Up to like & getrecommendations! Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s258157
Abstract: Background Increasing investigations indicate that long noncoding RNA (lncRNA) is responsible for diverse biological functions during the progression of cancer. However, its functions and underlying mechanisms remain elusive. Here, we investigated the MAFG-AS1- expression profile… read more here.
Keywords: progression; lasp1; esophageal squamous; mafg as1 ... See more keywords
The CXCR4-Dependent LASP1-Ago2 Interaction in Triple-Negative Breast Cancer
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DOI: 10.3390/cancers12092455
Abstract: Simple Summary CXCR4 is critically involved in triple-negative breast cancer metastasis. LASP1 was previously found to be necessary for CXCR4-dependent tumor cell invasion. Here we aimed to understand how LASP1 can have such a powerful… read more here.
Keywords: breast cancer; lasp1; triple negative; cxcr4 ... See more keywords
Lasp1 Expression Is Implicated in Embryonic Development of Zebrafish
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes14010035
Abstract: The LIM and SH3 domain protein 1 (LASP1) was originally identified in metastatic breast cancer and mainly characterized as a cytoskeleton protein overexpressed in various cancer types. At present, little is known about LASP1 expression… read more here.
Keywords: embryonic development; lasp1; development; expression implicated ... See more keywords