Liver-specific deletion of LASS2 delayed regeneration of mouse liver after partial hepatectomy.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.09.128
Abstract: The capacity of liver regeneration is critical for patients with liver diseases. However, cellular and molecular mechanisms of liver regeneration are still incompletely defined. Here, we assessed roles of LASS2 in liver regeneration following partial… read more here.
Keywords: lko mice; liver regeneration; regeneration; lass2 lko ... See more keywords
Overexpression of LASS2 inhibits proliferation and causes G0/G1 cell cycle arrest in papillary thyroid cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Cell International"
DOI: 10.1186/s12935-018-0649-1
Abstract: BackgroundThe aim of this study was to investigate the role of LAG1 longevity-assurance homologue 2 (LASS2) in papillary thyroid cancer (PTC).MethodsImmunohistochemistry staining was conducted to explore the expression levels of LASS2 in PTC tissues and… read more here.
Keywords: overexpression lass2; cell cycle; lass2; expression ... See more keywords
The role of LASS2 in regulating bladder cancer cell tumorigenicity in a nude mouse model
Sign Up to like & getrecommendations! Published in 2017 at "Oncology Letters"
DOI: 10.3892/ol.2017.6880
Abstract: Previous in vitro studies have demonstrated that LAG1 longevity assurance homolog 2 (LASS2) is a novel tumor suppressor gene that is significantly associated with the proliferation and invasion ability of tumor cells. However, the role… read more here.
Keywords: bladder cancer; growth; lass2; tumorigenicity ... See more keywords