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   Articles with "lassa" as a keyword



Modelling the effects of climate and human factor on Lassa fever distribution in Ondo State Nigeria

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recommendations! Published in 2025 at "International Journal of Biometeorology"

DOI: 10.1007/s00484-025-02996-3

Abstract: Lassa fever is an acute viral haemorrhagic disease caused by the Lassa virus. Transmission to humans primarily occurs through direct contact with Mastomys rats or via the ingestion of food or usage of household items… read more here.

Keywords: distribution; ondo state; state nigeria; lassa ... See more keywords
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Transplacental transfer of Lassa IgG antibodies in pregnant women in Southern Nigeria: A prospective hospital-based cohort study

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recommendations! Published in 2023 at "PLOS Neglected Tropical Diseases"

DOI: 10.1371/journal.pntd.0011209

Abstract: Background Evidence from previous studies suggest that Lassa fever, a viral haemorrhagic fever endemic to West Africa has high case fatalities, particularly in pregnancy. While there have been remarkable innovations in vaccine development, with some… read more here.

Keywords: transfer; igg antibodies; transplacental transfer; pregnant women ... See more keywords

MHC-I alleles mediate clearance and antibody response to the zoonotic Lassa virus in Mastomys rodent reservoirs

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recommendations! Published in 2024 at "PLOS Neglected Tropical Diseases"

DOI: 10.1371/journal.pntd.0011984

Abstract: West African Mastomys rodents are the primary reservoir of the zoonotic Lassa virus (LASV). The virus causes haemorrhagic Lassa fever and considerable mortality in humans. To date, the role of Mastomys immunogenetics in resistance to,… read more here.

Keywords: lasv; lassa; lassa virus; zoonotic lassa ... See more keywords

Expansion of myeloid suppressor cells and suppression of Lassa virus-specific T cells during fatal Lassa fever

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recommendations! Published in 2025 at "PLOS Pathogens"

DOI: 10.1371/journal.ppat.1013111

Abstract: Lassa fever is a highly lethal hemorrhagic fever endemic to West Africa. In the absence of efficient prophylactic or therapeutic countermeasures, it poses a substantial threat to public health in this region. The pathophysiological mechanisms… read more here.

Keywords: lassa; specific cells; lassa fever; lassa virus ... See more keywords

Knowledge, attitude and practice of Lassa fever prevention among adults in Bali Local Government Area, Taraba State, Nigeria

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recommendations! Published in 2024 at "Journal of Preventive Medicine and Hygiene"

DOI: 10.15167/2421-4248/jpmh2024.65.3.3225

Abstract: Summary Introduction Lassa fever (LF), a public health problem of great importance endemic in West Africa, is an acute and sometimes fatal viral haemorrhagic disease which leads to mortality. The current study assessed the knowledge,… read more here.

Keywords: among adults; adults bali; lassa; lassa fever ... See more keywords

Use of Favipiravir to Treat Lassa Virus Infection in Macaques

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recommendations! Published in 2018 at "Emerging Infectious Diseases"

DOI: 10.3201/eid2409.180233

Abstract: Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa fever is primarily supportive, although ribavirin has shown limited efficacy if administered early during infection. We tested favipiravir… read more here.

Keywords: infection; lassa; use favipiravir; lassa virus ... See more keywords

Pathogens that Cause Illness Clinically Indistinguishable from Lassa Fever, Nigeria, 2018

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recommendations! Published in 2022 at "Emerging Infectious Diseases"

DOI: 10.3201/eid2805.211153

Abstract: During the 2018 Lassa fever outbreak in Nigeria, samples from patients with suspected Lassa fever but negative Lassa virus PCR results were processed through custom gene expression array cards and metagenomic sequencing. Results demonstrated no… read more here.

Keywords: pathogens cause; cause illness; lassa fever; lassa ... See more keywords

Combating Lassa Fever in West African Sub-Region: Progress, Challenges, and Future Perspectives

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recommendations! Published in 2023 at "Viruses"

DOI: 10.3390/v15010146

Abstract: Lassa fever (LF) is a rodent-borne disease that threatens human health in the sub-region of West Africa where the zoonotic host of Lassa virus (LASV) is predominant. Currently, treatment options for LF are limited and… read more here.

Keywords: lassa; lasv; sub region; lassa fever ... See more keywords
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An Outbred Guinea Pig Disease Model for Lassa Fever Using a Host-Adapted Clade III Nigerian Lassa Virus

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recommendations! Published in 2023 at "Viruses"

DOI: 10.3390/v15030769

Abstract: Nigeria experiences annual outbreaks of Lassa fever (LF) with high case numbers. At least three clades of Lassa virus (LASV) have been documented in Nigeria, though recent outbreaks are most often associated with clade II… read more here.

Keywords: clade iii; guinea; model; lassa ... See more keywords

An epidemic model for control and possible elimination of Lassa fever

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recommendations! Published in 2023 at "Tamkang Journal of Mathematics"

DOI: 10.5556/j.tkjm.55.2024.5031

Abstract: Lassa fever is a deadly viral disease whose incubation period ranges from six to twenty-one days and about eighty percent of Lassa virus infection is asymptomatic. A deterministic model was formulated to quantify the transmission… read more here.

Keywords: lassa; possible elimination; model; lassa fever ... See more keywords