Characterization of the expression of LAT1 as a prognostic indicator and a therapeutic target in renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-53397-7
Abstract: Large neutral amino acid transporter 1 (LAT1, SLC7A5) is abundantly expressed in various types of cancer, and it has been thought to assist cancer progression through its activity for uptake of neutral amino acids. However,… read more here.
Keywords: renal cell; lat1 expression; cell carcinoma; expression ... See more keywords
mTORC2-AKT-LAT1 Signalling Participates in Methionine-induced β-CASEIN Expression in Mammary Epithelial Cells of Dairy Cows.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of animal physiology and animal nutrition"
DOI: 10.1111/jpn.13819
Abstract: This study investigated the role of the mammalian target of rapamycin complex 2 (mTORC2)-protein kinase B (AKT) signalling in methionine (Met)-induced L-type amino acid transporter 1 (LAT1) expression and milk protein production. Primary mammary epithelial… read more here.
Keywords: induced casein; met induced; expression; lat1 expression ... See more keywords
Glioblastoma Exhibits Inter-Individual Heterogeneity of TSPO and LAT1 Expression in Neoplastic and Parenchymal Cells
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DOI: 10.3390/ijms21020612
Abstract: Molecular imaging is essential for diagnosis and treatment planning for glioblastoma patients. Positron emission tomography (PET) with tracers for the detection of the solute carrier family 7 member 5 (SLC7A5; also known as the amino… read more here.
Keywords: tspo; tspo lat1; lat1 expression; gbm ... See more keywords