Articles with "lat1 targeted" as a keyword



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Structural Features Affecting the Interactions and Transportability of LAT1-Targeted Phenylalanine Drug Conjugates

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Published in 2022 at "Molecular Pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.2c00594

Abstract: L-type amino acid transporter 1 (LAT1) transfers essential amino acids across cell membranes. Owing to its predominant expression in the blood–brain barrier and tumor cells, LAT1 has been exploited for drug delivery and targeting to… read more here.

Keywords: bond; lat1 targeted; transportability; drug ... See more keywords