Mutations at the M2 and M3 Transmembrane Helices of the GABAARs α1 and β2 Subunits Affect Primarily Late Gating Transitions Including Opening/Closing and Desensitization
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DOI: 10.1021/acschemneuro.1c00151
Abstract: GABA type A receptors (GABAARs) belong to the pentameric ligand-gated ion channel (pLGIC) family and play a crucial role in mediating inhibition in the adult mammalian brain. Recently, a major progress in determining the static… read more here.
Keywords: transmembrane; opening closing; late gating; gating transitions ... See more keywords