Association of Titin Variations With Late-Onset Dilated Cardiomyopathy.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2021.5890
Abstract: Importance Dilated cardiomyopathy (DCM) is frequently caused by genetic factors. Studies identifying deleterious rare variants have predominantly focused on early-onset cases, and little is known about the genetic underpinnings of the growing numbers of patients… read more here.
Keywords: late onset; titin; onset dcm; dilated cardiomyopathy ... See more keywords
Incidence of and Neurodevelopmental Outcomes After Late-Onset Meningitis Among Children Born Extremely Preterm
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.45826
Abstract: Key Points Question What is the incidence of and outcomes following late-onset meningitis in children born extremely preterm? Findings In this cohort study of 13 372 children born extremely preterm, 1% of children were diagnosed with… read more here.
Keywords: born extremely; extremely preterm; onset meningitis; late onset ... See more keywords
Assessment of C-Reactive Protein Diagnostic Test Accuracy for Late-Onset Infection in Newborn Infants: A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA pediatrics"
DOI: 10.1001/jamapediatrics.2019.5669
Abstract: Importance Rapid and accurate diagnosis of late-onset infection in newborn infants could inform treatment decisions and avoid unnecessary administration of antibiotics. Objective To compare the accuracy of serum C-reactive protein (CRP) with that of microbiological… read more here.
Keywords: late onset; onset infection; infection; accuracy ... See more keywords
Proteomic profiling of sporadic late‐onset nemaline myopathy
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51527
Abstract: To define the proteomic profile of sporadic late‐onset nemaline myopathy (SLONM) and explore its pathogenesis. read more here.
Keywords: sporadic late; onset nemaline; nemaline myopathy; late onset ... See more keywords
Early‐onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late‐onset
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51689
Abstract: Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cognitive function in a well… read more here.
Keywords: alzheimer disease; onset; late onset; onset alzheimer ... See more keywords
PLA2G6-associated late-onset parkinsonism in a Sudanese family.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.51781
Abstract: INTRODUCTION The phospholipase A2 group VI gene (PLA2G6) encodes an enzyme that catalyzes the hydrolytic release of fatty acids from phospholipids. Four neurological disorders with infantile, juvenile, or early adult-onset are associated with PLA2G6 genetic… read more here.
Keywords: onset parkinsonism; onset; parkinsonism; late onset ... See more keywords
Whole genome sequencing of Caribbean Hispanic families with late‐onset Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.537
Abstract: To identify rare causal variants underlying known loci that segregate with late‐onset Alzheimer's disease (LOAD) in multiplex families. read more here.
Keywords: late onset; whole genome; alzheimer disease; genome sequencing ... See more keywords
Late Onset Hematological Complications post COVID-19: An Emerging Medical Problem for the Hematologist.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of hematology"
DOI: 10.1002/ajh.26384
Abstract: Coronavirus disease 19 (COVID-19) is considered as a multisystemic disease. Several studies have reported persistent symptoms or late-onset complications after acute COVID-19, including post-COVID-19 hematologic disorders. COVID-19- induced coagulopathy, an immunothrombotic state, has been linked… read more here.
Keywords: late onset; post covid; covid; onset hematological ... See more keywords
Liver transplantation in rare late‐onset ornithine transcarbamylase deficiency with central nervous system injury: A case report and review of the literature
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2765
Abstract: Ornithine transcarbamylase deficiency (OTCD) is a genetic metabolic disease. Its clinical manifestations are mainly central nervous system dysfunction caused by high blood ammonia. Late‐onset OTCD combined with central nervous system injury has a poor therapeutic… read more here.
Keywords: system; ornithine transcarbamylase; central nervous; nervous system ... See more keywords
Global longitudinal strain at 3 months after therapy can predict late cardiotoxicity in breast cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6039
Abstract: BACKGROUND Cancer therapy-related cardiovascular toxicity (CTR-CVT) is a major contributor to poor prognosis in breast cancer (BC) patients undergoing chemotherapy. Left ventricular global longitudinal strain (LV GLS) has predictive value for CTR-CVT, while few researchers… read more here.
Keywords: cancer; ctr cvt; strain; ctr ... See more keywords
Extreme late onset of genetic generalized epilepsy in older adults and the elderly: A cohort study and literature review
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia Open"
DOI: 10.1002/epi4.12671
Abstract: Rare case reports describe genetic generalized epilepsy (GGE) starting de novo in people ≥50 years of age (older adults and the elderly). We aimed to provide comprehensive detail of electro‐clinical findings of this extremely late‐onset GGE… read more here.
Keywords: adults elderly; older adults; epilepsy; generalized epilepsy ... See more keywords