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Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02090
Abstract: A high-yielding palladium-catalyzed C-S cross-coupling is presented for utilization in carbohydrate chemistry as a key transformation for attachment of a second chelating sulfur atom that allows the exploitation of a latent-active glycosylation strategy with Cu(OTf)2…
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Keywords:
latent active;
bond formation;
active glycosylation;
palladium catalyzed ... See more keywords
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Published in 2018 at "Chemical communications"
DOI: 10.1039/c7cc07332a
Abstract: Radical halogenation-mediated glycosylation using allyl glycosides as donors and as acceptors emerges to be an efficient and hither-to unknown glycosylation method, adhering to the concept of the latent-active methodology. Several di- and trisaccharides that possess…
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Keywords:
latent active;
methodology;
allyl glycosides;
radical halogenation ... See more keywords
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Published in 2019 at "mBio"
DOI: 10.1128/mbio.01037-19
Abstract: Tuberculosis is the infectious disease with the worldwide largest disease burden and there remains a great need for better diagnostic biomarkers to detect latent and active M. tuberculosis infection. RNA molecules hold great promise in…
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Keywords:
blood;
infection;
tuberculosis infection;
rna ... See more keywords
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Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.5611
Abstract: Background Testing the presence of latent or active tuberculosis using IGRA tests is necessary part of the diagnostic screening at risk individuals. QuantiFERON-TB Gold Plus (QFT-Plus) is a test for cell-mediated immune (CMI) responses to…
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Keywords:
qft plus;
latent active;
levels ifn;
tb1 tb2 ... See more keywords
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Published in 2018 at "Disease Markers"
DOI: 10.1155/2018/4687380
Abstract: One-fourth of the human population is estimated to have been exposed to Mycobacterium tuberculosis (Mtb) and carries the infection in its latent form. This latent infection presents a lifelong risk of developing active tuberculosis (TB)…
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Keywords:
latent active;
active tuberculosis;
infection;
susceptibility ... See more keywords
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Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.01174
Abstract: Tuberculosis (TB) has been the leading lethal infectious disease worldwide since 2014, and about one third of the world’s population has a latent TB infection (LTBI). This is largely attributed to the difficulties in diagnosis…
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Keywords:
small rna;
latent active;
hsa mir;
hsa ... See more keywords