Adolescent cannabis use and the later onset of bipolar disorder: protocol for a systematic review and meta‐analysis of prospective cohort studies
Sign Up to like & getrecommendations! Published in 2022 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12296
Abstract: Cannabis is used by adolescents worldwide. Adolescents are more susceptible to the psychological effects of cannabis because their brains are still developing. Cannabis use in adolescents has been reportedly associated with later onset of bipolar… read more here.
Keywords: onset bipolar; cannabis; later onset; bipolar disorder ... See more keywords
Physical processes controlling earlier and later onset of a typhoon season in the western North Pacific
Sign Up to like & getrecommendations! Published in 2017 at "Climate Dynamics"
DOI: 10.1007/s00382-017-4046-6
Abstract: The interannual variability of typhoon onset date in western North Pacific (WNP) during 1979–2015 is investigated. The average date in the earlier (later) onset group is early April (late July). A diagnosis of the genesis… read more here.
Keywords: typhoon; western north; specific humidity; north pacific ... See more keywords
An Integrated Safety Analysis of Infants and Children with Symptomatic Spinal Muscular Atrophy (SMA) Treated with Nusinersen in Seven Clinical Trials
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DOI: 10.1007/s40263-019-00656-w
Abstract: Treatment with nusinersen has demonstrated significant and clinically meaningful benefits in clinical trials in infants and children with spinal muscular atrophy (SMA). The objective of this analysis was to characterize the safety of nusinersen across… read more here.
Keywords: infants children; onset sma; safety; children symptomatic ... See more keywords
Characteristics associated with early- vs. later-onset adult diabetes: the CARDIA study.
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2021.109144
Abstract: AIMS Differences in risk profiles for individuals with early- (< 40 years old) vs. later-onset (≥ 40 years old) diabetes were examined. METHODS A nested case-control study design using 30-year longitudinal data from the Coronary… read more here.
Keywords: early onset; study; cardia study; later onset ... See more keywords
Correlation of Lyso-Gb3 levels in dried blood spots and sera from patients with classic and Later-Onset Fabry disease.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular genetics and metabolism"
DOI: 10.1016/j.ymgme.2017.06.006
Abstract: BACKGROUND Fabry disease (FD), an X-linked lysosomal storage disorder, results from the deficient activity of α-galactosidase A (α-Gal A) and the accumulation of its substrates, globotriaosylceramide (Gb3) and its deacylated derivative, globotriaosyl-sphingosine (Lyso-Gb3). Here, we… read more here.
Keywords: gb3 levels; classic later; gb3; lyso gb3 ... See more keywords
Novel RCBTB1 variants causing later-onset non-syndromic retinal dystrophy with macular chorioretinal atrophy
Sign Up to like & getrecommendations! Published in 2022 at "Ophthalmic Genetics"
DOI: 10.1080/13816810.2021.2023196
Abstract: ABSTRACT Background Variants in RCBTB1 were recently described to cause a retinal dystrophy with only eight families described to date and a predominant phenotype of macular atrophy and peripheral reticular degeneration. Here, we further evaluate… read more here.
Keywords: rcbtb1 variants; retinal dystrophy; later onset; atrophy ... See more keywords
Abstract 5760: Molecular, immune, and microbial profiles of early-onset, intermediate-onset, and later-onset CRCs
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5760
Abstract: Background: Despite heightened interest in early-onset CRC, little is known about the tumor molecular, immune, and microbial characteristics of early-onset CRC. It is also unclear whether CRCs diagnosed at or shortly after age 50 are… read more here.
Keywords: onset intermediate; early onset; onset; onset crc ... See more keywords
Abstract 13424: Demographic and Echocardiographic Predictors of Later-onset Cardiac Variant of Fabry Disease Among Chinese Patients With Left Ventricular Hypertrophy
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DOI: 10.1161/circ.142.suppl_3.13424
Abstract: Introduction: The genetic mutation IVS4+919G>A commonly found among Chinese is associated with later-onset cardiac variant of Fabry disease (FD). Patients with left ventricular hypertrophy (LVH) may be screened for FD by measuring plasma α-galactosidase activity.… read more here.
Keywords: among chinese; demographic echocardiographic; cardiac variant; onset cardiac ... See more keywords
Incident Early- and Later-Onset Type 2 Diabetes and Risk of Early- and Later-Onset Cancer: Prospective Cohort Study.
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DOI: 10.2337/dc22-1575
Abstract: OBJECTIVE We evaluated prospectively the association between incident early- (diagnosed before 40 years of age) and later-onset type 2 diabetes and early- (diagnosed before 50 years of age) and later-onset cancer risk. RESEARCH DESIGN AND… read more here.
Keywords: onset type; early onset; later onset; type diabetes ... See more keywords