Phorbol Esters from the Latex of Euphorbia umbellata: Bioguided Isolation of Highly Potent HIV-1 Latency Interrupters in Virus Reservoir Cells.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.0c01092
Abstract: Three known compounds, 20-deoxyphorbol-5β-hydroxy-12-tiglate-13-isobutyrate (1), 20-deoxyphorbol-5β-hydroxy-12-tiglate-13-phenylacetate (2), and 4-deoxy-4β-phorbol-12-tiglate-13-phenylacetate (3), were reisolated from the latex of Euphorbia umbellata through a bioguided fractionation process to target HIV-1 latency reactivation. The in vitro bioassay using infected T-cell… read more here.
Keywords: latency; euphorbia umbellata; hiv; latex euphorbia ... See more keywords
Isolation and Characterization of Mauritanicain, a Serine Protease from the Latex of Euphorbia mauritanica L.
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DOI: 10.1055/s-0042-117645
Abstract: A protease called Mauritanicain was isolated from the latex of Euphorbia mauritanica L. (Euphorbiaceae) by combining ion exchange chromatography, ultrafiltration, and gel filtration chromatography. It has a high proteolytic activity against casein. The activity was… read more here.
Keywords: latex euphorbia; serine protease; protease; euphorbia mauritanica ... See more keywords
New ingol-type diterpenes from the latex of Euphorbia resinifera
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DOI: 10.1080/10286020.2018.1498084
Abstract: Abstract Two new ingol-type diterpenes, euphoresins A–B (1–2), have been isolated from the methanol extract of Euphorbium, the latex of Euphorbia resinifera Berg. Their structures were established on the basis of extensive analyses of their… read more here.
Keywords: type diterpenes; latex euphorbia; diterpenes latex; new ingol ... See more keywords
The latex of Euphorbia tirucalli inhibits staphyloxanthin production and protects Tenebrio molitor larvae against Staphylococcus aureus infection
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DOI: 10.1080/14786419.2019.1582036
Abstract: Abstract The latex of Euphorbia tirucalli L. (LET) has great etnopharmacological relevance for several traditional communities. In this study, the in vitro and in vivo (using Tenebrio molitor larvae) antimicrobial effects of LET were evaluated.… read more here.
Keywords: molitor larvae; tenebrio molitor; latex euphorbia; euphorbia tirucalli ... See more keywords