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Differences in bioavailability and cognitive-enhancing activity exerted by different crystal polymorphs of latrepirdine (DimebonĀ®)

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Published in 2023 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2023.1091858

Abstract: Introduction: Pharmacokinetic characteristics as well as cognitive-enhancing nootropic activity of latrepirdine (DimebonĀ®) in relationship with its polymorphic forms have been studied in SD and Wistar rats. Methods: The pharmacokinetics of six polymorphs (A, B, C,… read more here.

Keywords: administration; bioavailability; activity; latrepirdine dimebon ... See more keywords