Abstract B06: Development of selective LATS1/LATS2 inhibitors for the pharmacologic modulation of the Hippo signaling pathway
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DOI: 10.1158/1557-3125.hippo19-b06
Abstract: We performed a large-scale profiling of currently available kinase inhibitors (KI) to identify “off-targets” that could be repurposed/repositioned as the starting point for the rational development of novel and selective kinase inhibitors against underdrugged targets.… read more here.
Keywords: hippo; selective lats1; lats1 lats2; lats2 inhibitors ... See more keywords