A Two-Layered Targeting Mechanism Underlies Nuclear RNA Sorting by the Human Exosome.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.01.068
Abstract: Degradation of transcripts in human nuclei is primarily facilitated by the RNA exosome. To obtain substrate specificity, the exosome is aided by adaptors; in the nucleoplasm, those adaptors are the nuclear exosome-targeting (NEXT) complex and the… read more here.
Keywords: targeting mechanism; two layered; layered targeting; exosome ... See more keywords