Inhibiting 12/15-lipoxygenase to treat acute stroke in permanent and tPA induced thrombolysis models
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DOI: 10.1016/j.brainres.2017.10.024
Abstract: 12/15-Lipoxygenase (12/15-LOX) contributes to the brain damage after middle cerebral artery occlusion (MCAO) in the acute phase of stroke. The aim of this study was to investigate the effects of a 12/15-LOX inhibitor, LOXBlock-1(LB1), in… read more here.
Keywords: fecl3 induced; tpa; distal mcao; lb1 ... See more keywords