Study of novel androgen receptor V770 variant in androgen insensitivity syndrome patients reveals the transitional state of the androgen receptor ligand binding domain homodimer
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DOI: 10.1002/pro.4599
Abstract: We report the discovery of the androgen receptor missense mutation V770D, that was found in two sisters suffering from complete androgen insensitivity. Experimental validation of AR V770 variants demonstrated that AR V770D was transcriptionally inactive… read more here.
Keywords: v770; lbd dimer; androgen receptor; dimerization ... See more keywords