Nuclear envelope protein LBR protects the genome from chromosomal instability and tumorigenesis.
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DOI: 10.1093/hmg/ddac235
Abstract: Lamin B Receptor (LBR) is an inner nuclear membrane protein that assembles the nuclear envelope post mitosis. Here we show that LBR depletion induces mitotic defects accompanied by recurrent chromosomal losses. In addition, LBR knockdown… read more here.
Keywords: nuclear envelope; lbr; lbr depletion; envelope protein ... See more keywords