The Machado–Joseph disease deubiquitylase ataxin‐3 interacts with LC3C/GABARAP and promotes autophagy
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DOI: 10.1111/acel.13051
Abstract: The pathology of spinocerebellar ataxia type 3, also known as Machado‐Joseph disease, is triggered by aggregation of toxic ataxin‐3 (ATXN3) variants containing expanded polyglutamine repeats. The physiological role of this deubiquitylase, however, remains largely unclear.… read more here.
Keywords: joseph disease; machado joseph; deubiquitylase; lc3c gabarap ... See more keywords