FRI0297 Macrophage-derived lcn2 contributes to development of lupus nephritis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.3599
Abstract: Background Renal involvement is a major concern in systemic lupus erythematosus (SLE). Many findings have indicated that plasma and urinary LCN2 is a potential marker of the presence and severity of renal involvement in SLE.… read more here.
Keywords: lcn2; pathology; lupus nephritis; lcn2 levels ... See more keywords
Proteasome inhibition suppresses the induction of lipocalin-2 upon systemic lipopolysaccharide challenge in mice
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Brain"
DOI: 10.1186/s13041-024-01147-w
Abstract: Lipocalin-2 (Lcn2), a protein secreted by immune-activated cells, including reactive astrocytes, is detrimental to the brain and induces neurodegeneration. We previously showed that Lcn2 levels are reduced in primary mouse astrocytes after treatment with the… read more here.
Keywords: mice; brain; lcn2 levels; challenge ... See more keywords