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Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.06.015
Abstract: BACKGROUND AND AIMS Lipocalin-2 (Lcn2) is a glycoprotein which can be secreted by immune cells. Several studies in humans have suggested Lcn2 can be used as a biomarker for the detection of unstable atherosclerotic lesions,…
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Keywords:
lipocalin contributes;
ldlr lcn2;
atherosclerotic lesions;
lcn2 mice ... See more keywords
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Published in 2018 at "International Journal of Obesity"
DOI: 10.1038/s41366-018-0171-5
Abstract: Background:Lipocalin-2 (LCN2) is widely expressed in the organism with pleiotropic roles. In particular, its overexpression correlates with tissue stress conditions including inflammation, metabolic disorders, chronic diseases and cancer.Objectives:To assess the effects of systemic LCN2 overexpression…
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Keywords:
lcn2 mice;
overexpression;
anthropometric glucometabolic;
adipose tissue ... See more keywords
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Published in 2019 at "Journal of Animal Science"
DOI: 10.1093/jas/skz258.035
Abstract: Lipocalin 2 (Lcn2) is an essential component of the innate immune system and exerts significant immunomodulatory effects in vitro. The aim of current study was to investigate the expression profile of Lcn2 during inflammatory process…
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Keywords:
anti inflammatory;
lcn2;
inflammatory responses;
alleviating inflammatory ... See more keywords
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Published in 2021 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s328916
Abstract: Purpose Lipocalin-2 (Lcn2) is an acute-phase protein and elevated in several inflammatory diseases. This study aimed to determine whether Lcn2 alleviates inflammation and explore the underlying cellular mechanisms. Methods C57BL/6 Lcn2-deficient (Lcn2−/-) male mice were…
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Keywords:
macrophage;
mice;
pro inflammatory;
lcn2 mice ... See more keywords