Lipocalin-2 contributes to experimental atherosclerosis in a stage-dependent manner.
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.06.015
Abstract: BACKGROUND AND AIMS Lipocalin-2 (Lcn2) is a glycoprotein which can be secreted by immune cells. Several studies in humans have suggested Lcn2 can be used as a biomarker for the detection of unstable atherosclerotic lesions,… read more here.
Keywords: lipocalin contributes; ldlr lcn2; atherosclerotic lesions; lcn2 mice ... See more keywords
Anthropometric and glucometabolic changes in an aged mouse model of lipocalin-2 overexpression
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Obesity"
DOI: 10.1038/s41366-018-0171-5
Abstract: Background:Lipocalin-2 (LCN2) is widely expressed in the organism with pleiotropic roles. In particular, its overexpression correlates with tissue stress conditions including inflammation, metabolic disorders, chronic diseases and cancer.Objectives:To assess the effects of systemic LCN2 overexpression… read more here.
Keywords: lcn2 mice; overexpression; anthropometric glucometabolic; adipose tissue ... See more keywords
13 Lipocalin 2 exerts protective activity by alleviating inflammatory responses
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DOI: 10.1093/jas/skz258.035
Abstract: Lipocalin 2 (Lcn2) is an essential component of the innate immune system and exerts significant immunomodulatory effects in vitro. The aim of current study was to investigate the expression profile of Lcn2 during inflammatory process… read more here.
Keywords: anti inflammatory; lcn2; inflammatory responses; alleviating inflammatory ... See more keywords
Lipocalin-2 Alleviates LPS-Induced Inflammation Through Alteration of Macrophage Properties
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DOI: 10.2147/jir.s328916
Abstract: Purpose Lipocalin-2 (Lcn2) is an acute-phase protein and elevated in several inflammatory diseases. This study aimed to determine whether Lcn2 alleviates inflammation and explore the underlying cellular mechanisms. Methods C57BL/6 Lcn2-deficient (Lcn2−/-) male mice were… read more here.
Keywords: macrophage; mice; pro inflammatory; lcn2 mice ... See more keywords